Fletcher RS - Search Results

1

Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.

Borkow G, Fletcher RS, Barnard J, Arion D, Motakis D, Dmitrienko GI, Parniak MA. Borkow G, et al. Among authors: fletcher rs. Biochemistry. 1997 Mar 18;36(11):3179-85. doi: 10.1021/bi9624696. Biochemistry. 1997. PMID: 9115994

2

Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones.

Arion D, Sluis-Cremer N, Min KL, Abram ME, Fletcher RS, Parniak MA. Arion D, et al. Among authors: fletcher rs. J Biol Chem. 2002 Jan 11;277(2):1370-4. doi: 10.1074/jbc.M110254200. Epub 2001 Oct 29. J Biol Chem. 2002. PMID: 11684697 Free article.

3

Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase.

Fletcher RS, Holleschak G, Nagy E, Arion D, Borkow G, Gu Z, Wainberg MA, Parniak MA. Fletcher RS, et al. Protein Expr Purif. 1996 Feb;7(1):27-32. doi: 10.1006/prep.1996.0004. Protein Expr Purif. 1996. PMID: 9172779

4

Differences in the inhibition of human immunodeficiency virus type 1 reverse transcriptase DNA polymerase activity by analogs of nevirapine and [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2",2"-dioxide] (TSAO).

Arion D, Fletcher RS, Borkow G, Camarasa MJ, Balzarini J, Dmitrienko GI, Parniak MA. Arion D, et al. Among authors: fletcher rs. Mol Pharmacol. 1996 Nov;50(5):1057-64. Mol Pharmacol. 1996. PMID: 8913335

5

Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds.

Fletcher RS, Arion D, Borkow G, Wainberg MA, Dmitrienko GI, Parniak MA. Fletcher RS, et al. Biochemistry. 1995 Aug 15;34(32):10106-12. doi: 10.1021/bi00032a002. Biochemistry. 1995. PMID: 7543775

6

The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro.

Gu Z, Fletcher RS, Arts EJ, Wainberg MA, Parniak MA. Gu Z, et al. Among authors: fletcher rs. J Biol Chem. 1994 Nov 11;269(45):28118-22. J Biol Chem. 1994. PMID: 7525567 Free article.

7

Carboxanilide derivative non-nucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme.

Fletcher RS, Syed K, Mithani S, Dmitrienko GI, Parniak MA. Fletcher RS, et al. Biochemistry. 1995 Apr 4;34(13):4346-53. doi: 10.1021/bi00013a025. Biochemistry. 1995. PMID: 7535561

8

Functional correlation of genome-wide DNA methylation profiles in genetic neurodevelopmental disorders.

Levy MA, Relator R, McConkey H, Pranckeviciene E, Kerkhof J, Barat-Houari M, Bargiacchi S, Biamino E, Bralo MP, Cappuccio G, Ciolfi A, Clarke A, DuPont BR, Elting MW, Faivre L, Fee T, Ferilli M, Fletcher RS, Cherick F, Foroutan A, Friez MJ, Gervasini C, Haghshenas S, Hilton BA, Jenkins Z, Kaur S, Lewis S, Louie RJ, Maitz S, Milani D, Morgan AT, Oegema R, Østergaard E, Pallares NR, Piccione M, Plomp AS, Poulton C, Reilly J, Rius R, Robertson S, Rooney K, Rousseau J, Santen GWE, Santos-Simarro F, Schijns J, Squeo GM, John MS, Thauvin-Robinet C, Traficante G, van der Sluijs PJ, Vergano SA, Vos N, Walden KK, Azmanov D, Balci TB, Banka S, Gecz J, Henneman P, Lee JA, Mannens MMAM, Roscioli T, Siu V, Amor DJ, Baynam G, Bend EG, Boycott K, Brunetti-Pierri N, Campeau PM, Campion D, Christodoulou J, Dyment D, Esber N, Fahrner JA, Fleming MD, Genevieve D, Heron D, Husson T, Kernohan KD, McNeill A, Menke LA, Merla G, Prontera P, Rockman-Greenberg C, Schwartz C, Skinner SA, Stevenson RE, Vincent M, Vitobello A, Tartaglia M, Alders M, Tedder ML, Sadikovic B. Levy MA, et al. Among authors: fletcher rs. Hum Mutat. 2022 Jul 29. doi: 10.1002/humu.24446. Online ahead of print. Hum Mutat. 2022. PMID: 35904121

9

Novel diagnostic DNA methylation episignatures expand and refine the epigenetic landscapes of Mendelian disorders.

Levy MA, McConkey H, Kerkhof J, Barat-Houari M, Bargiacchi S, Biamino E, Bralo MP, Cappuccio G, Ciolfi A, Clarke A, DuPont BR, Elting MW, Faivre L, Fee T, Fletcher RS, Cherik F, Foroutan A, Friez MJ, Gervasini C, Haghshenas S, Hilton BA, Jenkins Z, Kaur S, Lewis S, Louie RJ, Maitz S, Milani D, Morgan AT, Oegema R, Østergaard E, Pallares NR, Piccione M, Pizzi S, Plomp AS, Poulton C, Reilly J, Relator R, Rius R, Robertson S, Rooney K, Rousseau J, Santen GWE, Santos-Simarro F, Schijns J, Squeo GM, St John M, Thauvin-Robinet C, Traficante G, van der Sluijs PJ, Vergano SA, Vos N, Walden KK, Azmanov D, Balci T, Banka S, Gecz J, Henneman P, Lee JA, Mannens MMAM, Roscioli T, Siu V, Amor DJ, Baynam G, Bend EG, Boycott K, Brunetti-Pierri N, Campeau PM, Christodoulou J, Dyment D, Esber N, Fahrner JA, Fleming MD, Genevieve D, Kerrnohan KD, McNeill A, Menke LA, Merla G, Prontera P, Rockman-Greenberg C, Schwartz C, Skinner SA, Stevenson RE, Vitobello A, Tartaglia M, Alders M, Tedder ML, Sadikovic B. Levy MA, et al. Among authors: fletcher rs. HGG Adv. 2021 Dec 3;3(1):100075. doi: 10.1016/j.xhgg.2021.100075. eCollection 2022 Jan 13. HGG Adv. 2021. PMID: 35047860 Free PMC article.

10

Near complete deletion of KMT2D in a college student.

Gooch C, Souder JP, Tedder ML, Kerkhof J, Lee JA, Louie RJ, Sadikovic B, Fletcher RS, Robin NH. Gooch C, et al. Among authors: fletcher rs. Am J Med Genet A. 2022 May;188(5):1550-1555. doi: 10.1002/ajmg.a.62652. Epub 2022 Jan 18. Am J Med Genet A. 2022. PMID: 35040536

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