Fletterick RJ - Search Results

1

Engineered metalloregulation in enzymes.

Higaki JN, Fletterick RJ, Craik CS. Higaki JN, et al. Among authors: fletterick rj. Trends Biochem Sci. 1992 Mar;17(3):100-4. doi: 10.1016/0968-0004(92)90245-5. Trends Biochem Sci. 1992. PMID: 1329276 Review.

2

Regulation of serine protease activity by an engineered metal switch.

Higaki JN, Haymore BL, Chen S, Fletterick RJ, Craik CS. Higaki JN, et al. Among authors: fletterick rj. Biochemistry. 1990 Sep 18;29(37):8582-6. doi: 10.1021/bi00489a012. Biochemistry. 1990. PMID: 2125468

3

Structure of an engineered, metal-actuated switch in trypsin.

McGrath ME, Haymore BL, Summers NL, Craik CS, Fletterick RJ. McGrath ME, et al. Among authors: fletterick rj. Biochemistry. 1993 Mar 2;32(8):1914-9. doi: 10.1021/bi00059a005. Biochemistry. 1993. PMID: 8448149

4

The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity.

Waugh SM, Harris JL, Fletterick R, Craik CS. Waugh SM, et al. Nat Struct Biol. 2000 Sep;7(9):762-5. doi: 10.1038/78992. Nat Struct Biol. 2000. PMID: 10966646

5

The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.

Bell JK, Goetz DH, Mahrus S, Harris JL, Fletterick RJ, Craik CS. Bell JK, et al. Among authors: fletterick rj. Nat Struct Biol. 2003 Jul;10(7):527-34. doi: 10.1038/nsb944. Nat Struct Biol. 2003. PMID: 12819769

6

The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli.

McGrath ME, Hines WM, Sakanari JA, Fletterick RJ, Craik CS. McGrath ME, et al. Among authors: fletterick rj. J Biol Chem. 1991 Apr 5;266(10):6620-5. J Biol Chem. 1991. PMID: 2007606 Free article.

7

Crystallographic analysis of trypsin-G226A. A specificity pocket mutant of rat trypsin with altered binding and catalysis.

Wilke ME, Higaki JN, Craik CS, Fletterick RJ. Wilke ME, et al. Among authors: fletterick rj. J Mol Biol. 1991 Jun 5;219(3):525-32. doi: 10.1016/0022-2836(91)90191-8. J Mol Biol. 1991. PMID: 2051486

8

Crystal structures of two engineered thiol trypsins.

McGrath ME, Wilke ME, Higaki JN, Craik CS, Fletterick RJ. McGrath ME, et al. Among authors: fletterick rj. Biochemistry. 1989 Nov 28;28(24):9264-70. doi: 10.1021/bi00450a005. Biochemistry. 1989. PMID: 2611228

9

Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI.

Perona JJ, Tsu CA, Craik CS, Fletterick RJ. Perona JJ, et al. Among authors: fletterick rj. J Mol Biol. 1993 Apr 5;230(3):919-33. doi: 10.1006/jmbi.1993.1210. J Mol Biol. 1993. PMID: 7683059

10

Engineered metal regulation of trypsin specificity.

Willett WS, Gillmor SA, Perona JJ, Fletterick RJ, Craik CS. Willett WS, et al. Among authors: fletterick rj. Biochemistry. 1995 Feb 21;34(7):2172-80. doi: 10.1021/bi00007a010. Biochemistry. 1995. PMID: 7857928

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