Fleuren W - Search Results

1

A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain.

Folkertsma S, van Noort P, Van Durme J, Joosten HJ, Bettler E, Fleuren W, Oliveira L, Horn F, de Vlieg J, Vriend G. Folkertsma S, et al. Among authors: fleuren w. J Mol Biol. 2004 Aug 6;341(2):321-35. doi: 10.1016/j.jmb.2004.05.075. J Mol Biol. 2004. PMID: 15276826 Review.

2

ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs.

Sanders MP, Fleuren WW, Verhoeven S, van den Beld S, Alkema W, de Vlieg J, Klomp JP. Sanders MP, et al. Among authors: fleuren ww. BMC Bioinformatics. 2011 Aug 10;12:332. doi: 10.1186/1471-2105-12-332. BMC Bioinformatics. 2011. PMID: 21831265 Free PMC article.

3

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W. Fleuren WW, et al. Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022. Epub 2013 Mar 19. Arch Physiol Biochem. 2013. PMID: 23506355 Free PMC article.

4

CoPub update: CoPub 5.0 a text mining system to answer biological questions.

Fleuren WW, Verhoeven S, Frijters R, Heupers B, Polman J, van Schaik R, de Vlieg J, Alkema W. Fleuren WW, et al. Nucleic Acids Res. 2011 Jul;39(Web Server issue):W450-4. doi: 10.1093/nar/gkr310. Epub 2011 May 27. Nucleic Acids Res. 2011. PMID: 21622961 Free PMC article.

5

Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining.

Fleuren WW, Toonen EJ, Verhoeven S, Frijters R, Hulsen T, Rullmann T, van Schaik R, de Vlieg J, Alkema W. Fleuren WW, et al. BioData Min. 2013 Feb 4;6(1):2. doi: 10.1186/1756-0381-6-2. BioData Min. 2013. PMID: 23379763 Free PMC article.

6

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.

Frijters R, Fleuren W, Toonen EJ, Tuckermann JP, Reichardt HM, van der Maaden H, van Elsas A, van Lierop MJ, Dokter W, de Vlieg J, Alkema W. Frijters R, et al. Among authors: fleuren w. BMC Genomics. 2010 Jun 5;11:359. doi: 10.1186/1471-2164-11-359. BMC Genomics. 2010. PMID: 20525385 Free PMC article.

7

Application of text mining in the biomedical domain.

Fleuren WW, Alkema W. Fleuren WW, et al. Methods. 2015 Mar;74:97-106. doi: 10.1016/j.ymeth.2015.01.015. Epub 2015 Jan 30. Methods. 2015. PMID: 25641519 Review.

8

Identification of gene signatures for prednisolone-induced metabolic dysfunction in collagen-induced arthritic mice.

Ellero-Simatos S, Fleuren WW, Bauerschmidt S, Dokter WH, Toonen EJ. Ellero-Simatos S, et al. Among authors: fleuren ww. Pharmacogenomics. 2014 Apr;15(5):629-41. doi: 10.2217/pgs.14.3. Pharmacogenomics. 2014. PMID: 24798720

9

Prednisolone-induced changes in gene-expression profiles in healthy volunteers.

Toonen EJ, Fleuren WW, Nässander U, van Lierop MJ, Bauerschmidt S, Dokter WH, Alkema W. Toonen EJ, et al. Among authors: fleuren ww. Pharmacogenomics. 2011 Jul;12(7):985-98. doi: 10.2217/pgs.11.34. Epub 2011 Jun 2. Pharmacogenomics. 2011. PMID: 21635145 Clinical Trial.

10

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling.

Smeets RL, Fleuren WW, He X, Vink PM, Wijnands F, Gorecka M, Klop H, Bauerschmidt S, Garritsen A, Koenen HJ, Joosten I, Boots AM, Alkema W. Smeets RL, et al. Among authors: fleuren ww. BMC Immunol. 2012 Mar 14;13:12. doi: 10.1186/1471-2172-13-12. BMC Immunol. 2012. PMID: 22413885 Free PMC article.

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