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Hematopoietic stem and progenitor cell mobilization in mice and humans by a first-in-class mirror-image oligonucleotide inhibitor of CXCL12.
Vater A, Sahlmann J, Kröger N, Zöllner S, Lioznov M, Maasch C, Buchner K, Vossmeyer D, Schwoebel F, Purschke WG, Vonhoff S, Kruschinski A, Hübel K, Humphrey M, Klussmann S, Fliegert F. Vater A, et al. Among authors: fliegert f. Clin Pharmacol Ther. 2013 Jul;94(1):150-7. doi: 10.1038/clpt.2013.58. Epub 2013 Mar 19. Clin Pharmacol Ther. 2013. PMID: 23588307
Safety, Tolerability, and Pharmacokinetics of IMU-935, a Novel Inverse Agonist of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γt: Results From a Double-Blind, Placebo-Controlled, First-in-Human Phase 1 Study.
Polasek TM, Leelasena I, Betscheider I, Marolt M, Kohlhof H, Vitt D, Fliegert F, Muehler AR. Polasek TM, et al. Among authors: fliegert f. Clin Pharmacol Drug Dev. 2023 May;12(5):525-534. doi: 10.1002/cpdd.1243. Epub 2023 Mar 20. Clin Pharmacol Drug Dev. 2023. PMID: 36938862 Clinical Trial.
The ADP-ribosylation factor (ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase D.
Schürmann A, Schmidt M, Asmus M, Bayer S, Fliegert F, Koling S, Massmann S, Schilf C, Subauste MC, Voss M, Jakobs KH, Joost HG. Schürmann A, et al. Among authors: fliegert f. J Biol Chem. 1999 Apr 2;274(14):9744-51. doi: 10.1074/jbc.274.14.9744. J Biol Chem. 1999. PMID: 10092663 Free article.