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Adipose tissue as an endocrine organ.
Ahima RS, Flier JS. Ahima RS, et al. Among authors: flier js. Trends Endocrinol Metab. 2000 Oct;11(8):327-32. doi: 10.1016/s1043-2760(00)00301-5. Trends Endocrinol Metab. 2000. PMID: 10996528 Review.
Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.
Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E. Segal-Lieberman G, et al. Among authors: flier js. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. doi: 10.1073/pnas.1633636100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897241 Free PMC article.
Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice.
Morton NM, Paterson JM, Masuzaki H, Holmes MC, Staels B, Fievet C, Walker BR, Flier JS, Mullins JJ, Seckl JR. Morton NM, et al. Among authors: flier js. Diabetes. 2004 Apr;53(4):931-8. doi: 10.2337/diabetes.53.4.931. Diabetes. 2004. PMID: 15047607
Attenuation of leptin and insulin signaling by SOCS proteins.
Howard JK, Flier JS. Howard JK, et al. Among authors: flier js. Trends Endocrinol Metab. 2006 Nov;17(9):365-71. doi: 10.1016/j.tem.2006.09.007. Epub 2006 Sep 28. Trends Endocrinol Metab. 2006. PMID: 17010638 Review.
Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.
Shinyama H, Masuzaki H, Fang H, Flier JS. Shinyama H, et al. Among authors: flier js. Endocrinology. 2003 Apr;144(4):1301-14. doi: 10.1210/en.2002-220931. Endocrinology. 2003. PMID: 12639913
Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo.
Domouzoglou EM, Fisher FM, Astapova I, Fox EC, Kharitonenkov A, Flier JS, Hollenberg AN, Maratos-Flier E. Domouzoglou EM, et al. Among authors: flier js. Endocrinology. 2014 May;155(5):2031-40. doi: 10.1210/en.2013-1902. Epub 2014 Feb 24. Endocrinology. 2014. PMID: 24564398 Free PMC article.
Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance.
Shi H, Cave B, Inouye K, Bjørbaek C, Flier JS. Shi H, et al. Among authors: flier js. Diabetes. 2006 Mar;55(3):699-707. doi: 10.2337/diabetes.55.03.06.db05-0841. Diabetes. 2006. PMID: 16505233
Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis.
Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E. Badman MK, et al. Among authors: flier js. Endocrinology. 2009 Nov;150(11):4931-40. doi: 10.1210/en.2009-0532. Epub 2009 Oct 9. Endocrinology. 2009. PMID: 19819944 Free PMC article.
Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.
Zhang R, Maratos-Flier E, Flier JS. Zhang R, et al. Among authors: flier js. Endocrinology. 2009 Jul;150(7):3076-82. doi: 10.1210/en.2009-0108. Epub 2009 Apr 9. Endocrinology. 2009. PMID: 19359377 Free PMC article.
PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.
Kershaw EE, Schupp M, Guan HP, Gardner NP, Lazar MA, Flier JS. Kershaw EE, et al. Among authors: flier js. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1736-45. doi: 10.1152/ajpendo.00122.2007. Epub 2007 Sep 11. Am J Physiol Endocrinol Metab. 2007. PMID: 17848638 Free PMC article.
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