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282 results
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Obesity wars: molecular progress confronts an expanding epidemic.
Flier JS. Flier JS. Cell. 2004 Jan 23;116(2):337-50. doi: 10.1016/s0092-8674(03)01081-x. Cell. 2004. PMID: 14744442 Review.
Unraveling the central nervous system pathways underlying responses to leptin.
Elmquist JK, Maratos-Flier E, Saper CB, Flier JS. Elmquist JK, et al. Among authors: flier js. Nat Neurosci. 1998 Oct;1(6):445-50. doi: 10.1038/2164. Nat Neurosci. 1998. PMID: 10196541 Review.
Energy homeostasis and body weight.
Flier J, Maratos-Flier E. Flier J, et al. Curr Biol. 2000 Mar 23;10(6):R215-7. doi: 10.1016/s0960-9822(00)00393-6. Curr Biol. 2000. PMID: 10744985 Review. No abstract available.
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.
Howard JK, Cave BJ, Oksanen LJ, Tzameli I, Bjørbaek C, Flier JS. Howard JK, et al. Among authors: flier js. Nat Med. 2004 Jul;10(7):734-8. doi: 10.1038/nm1072. Epub 2004 Jun 27. Nat Med. 2004. PMID: 15220914
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state.
Fisher FM, Chui PC, Antonellis PJ, Bina HA, Kharitonenkov A, Flier JS, Maratos-Flier E. Fisher FM, et al. Among authors: flier js. Diabetes. 2010 Nov;59(11):2781-9. doi: 10.2337/db10-0193. Epub 2010 Aug 3. Diabetes. 2010. PMID: 20682689 Free PMC article.
Leptin's Physiologic Role: Does the Emperor of Energy Balance Have No Clothes?
Flier JS, Maratos-Flier E. Flier JS, et al. Cell Metab. 2017 Jul 5;26(1):24-26. doi: 10.1016/j.cmet.2017.05.013. Epub 2017 Jun 22. Cell Metab. 2017. PMID: 28648981
Hormone resistance in diabetes and obesity: insulin, leptin, and FGF21.
Flier JS. Flier JS. Yale J Biol Med. 2012 Sep;85(3):405-14. Epub 2012 Sep 25. Yale J Biol Med. 2012. PMID: 23012588 Free PMC article.
Neuroscience. The fat-brain axis enters a new dimension.
Elmquist JK, Flier JS. Elmquist JK, et al. Among authors: flier js. Science. 2004 Apr 2;304(5667):63-4. doi: 10.1126/science.1096746. Science. 2004. PMID: 15064411 No abstract available.
Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.
Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E. Segal-Lieberman G, et al. Among authors: flier js. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. doi: 10.1073/pnas.1633636100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897241 Free PMC article.
Starvation in the Midst of Plenty: Reflections on the History and Biology of Insulin and Leptin.
Flier JS. Flier JS. Endocr Rev. 2019 Feb 1;40(1):1-16. doi: 10.1210/er.2018-00179. Endocr Rev. 2019. PMID: 30357355 Free PMC article. Review.
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