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Mice lacking melanin-concentrating hormone are hypophagic and lean.
Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E. Shimada M, et al. Nature. 1998 Dec 17;396(6712):670-4. doi: 10.1038/25341. Nature. 1998. PMID: 9872314
Unraveling the central nervous system pathways underlying responses to leptin.
Elmquist JK, Maratos-Flier E, Saper CB, Flier JS. Elmquist JK, et al. Nat Neurosci. 1998 Oct;1(6):445-50. doi: 10.1038/2164. Nat Neurosci. 1998. PMID: 10196541 Review.
Energy homeostasis and body weight.
Flier J, Maratos-Flier E. Flier J, et al. Curr Biol. 2000 Mar 23;10(6):R215-7. doi: 10.1016/s0960-9822(00)00393-6. Curr Biol. 2000. PMID: 10744985 Review. No abstract available.
Physiology: is brain sympathetic to bone?
Flier JS. Flier JS. Nature. 2002 Dec 12;420(6916):619, 621-22. doi: 10.1038/420619a. Nature. 2002. PMID: 12478275 No abstract available.
Leptin's Physiologic Role: Does the Emperor of Energy Balance Have No Clothes?
Flier JS, Maratos-Flier E. Flier JS, et al. Cell Metab. 2017 Jul 5;26(1):24-26. doi: 10.1016/j.cmet.2017.05.013. Epub 2017 Jun 22. Cell Metab. 2017. PMID: 28648981
Neuroscience. The fat-brain axis enters a new dimension.
Elmquist JK, Flier JS. Elmquist JK, et al. Science. 2004 Apr 2;304(5667):63-4. doi: 10.1126/science.1096746. Science. 2004. PMID: 15064411 No abstract available.
Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.
Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E. Segal-Lieberman G, et al. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. doi: 10.1073/pnas.1633636100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897241 Free PMC article.
Obesity wars: molecular progress confronts an expanding epidemic.
Flier JS. Flier JS. Cell. 2004 Jan 23;116(2):337-50. doi: 10.1016/s0092-8674(03)01081-x. Cell. 2004. PMID: 14744442 Review.
Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance.
Briancon N, McNay DE, Maratos-Flier E, Flier JS. Briancon N, et al. Diabetes. 2010 Dec;59(12):3074-84. doi: 10.2337/db10-0481. Epub 2010 Sep 28. Diabetes. 2010. PMID: 20876718 Free PMC article.
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