Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

10 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Catching a DUB in the act: novel ubiquitin-based active site directed probes.
Ekkebus R, Flierman D, Geurink PP, Ovaa H. Ekkebus R, et al. Among authors: flierman d. Curr Opin Chem Biol. 2014 Dec;23:63-70. doi: 10.1016/j.cbpa.2014.10.005. Curr Opin Chem Biol. 2014. PMID: 25461387 Free PMC article. Review.
Release of Enzymatically Active Deubiquitinating Enzymes upon Reversible Capture by Disulfide Ubiquitin Reagents.
de Jong A, Witting K, Kooij R, Flierman D, Ovaa H. de Jong A, et al. Among authors: flierman d. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12967-12970. doi: 10.1002/anie.201706738. Epub 2017 Sep 12. Angew Chem Int Ed Engl. 2017. PMID: 28841265 Free PMC article.
Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets.
Flierman D, van der Heden van Noort GJ, Ekkebus R, Geurink PP, Mevissen TE, Hospenthal MK, Komander D, Ovaa H. Flierman D, et al. Cell Chem Biol. 2016 Apr 21;23(4):472-82. doi: 10.1016/j.chembiol.2016.03.009. Epub 2016 Apr 7. Cell Chem Biol. 2016. PMID: 27066941 Free PMC article.
USP7: combining tools towards selectivity.
Gjonaj L , Sapmaz A , González-Prieto R , Vertegaal ACO , Flierman D , Ovaa H . Gjonaj L , et al. Among authors: flierman d. Chem Commun (Camb). 2019 Apr 25;55(35):5075-5078. doi: 10.1039/c9cc00969h. Chem Commun (Camb). 2019. PMID: 30972393
Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol.
Shamu CE, Flierman D, Ploegh HL, Rapoport TA, Chau V. Shamu CE, et al. Among authors: flierman d. Mol Biol Cell. 2001 Aug;12(8):2546-55. doi: 10.1091/mbc.12.8.2546. Mol Biol Cell. 2001. PMID: 11514634 Free PMC article.
Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane.
Flierman D, Ye Y, Dai M, Chau V, Rapoport TA. Flierman D, et al. J Biol Chem. 2003 Sep 12;278(37):34774-82. doi: 10.1074/jbc.M303360200. Epub 2003 Jun 17. J Biol Chem. 2003. PMID: 12813030 Free article.
E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system.
Flierman D, Coleman CS, Pickart CM, Rapoport TA, Chau V. Flierman D, et al. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11589-94. doi: 10.1073/pnas.0605215103. Epub 2006 Jul 25. Proc Natl Acad Sci U S A. 2006. PMID: 16868077 Free PMC article.
Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55.
Karpus ON, Veninga H, Hoek RM, Flierman D, van Buul JD, Vandenakker CC, vanBavel E, Medof ME, van Lier RA, Reedquist KA, Hamann J. Karpus ON, et al. Among authors: flierman d. J Immunol. 2013 Apr 1;190(7):3740-8. doi: 10.4049/jimmunol.1202192. Epub 2013 Feb 27. J Immunol. 2013. PMID: 23447688 Free article.
Development of a DUB-selective fluorogenic substrate.
Gjonaj L, Sapmaz A, Flierman D, Janssen GMC, van Veelen PA, Ovaa H. Gjonaj L, et al. Among authors: flierman d. Chem Sci. 2019 Sep 30;10(44):10290-10296. doi: 10.1039/c9sc02226k. eCollection 2019 Nov 28. Chem Sci. 2019. PMID: 32110315 Free PMC article.
Diubiquitin-Based NMR Analysis: Interactions Between Lys6-Linked diUb and UBA Domain of UBXN1.
Shahul Hameed D, van Tilburg GBA, Merkx R, Flierman D, Wienk H, El Oualid F, Hofmann K, Boelens R, Ovaa H. Shahul Hameed D, et al. Among authors: flierman d. Front Chem. 2020 Jan 22;7:921. doi: 10.3389/fchem.2019.00921. eCollection 2019. Front Chem. 2020. PMID: 32039147 Free PMC article.