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The once-daily human GLP-1 analogue liraglutide impacts appetite and energy intake in patients with type 2 diabetes after short-term treatment.
Flint A, Kapitza C, Zdravkovic M. Flint A, et al. Diabetes Obes Metab. 2013 Oct;15(10):958-62. doi: 10.1111/dom.12108. Epub 2013 Apr 23. Diabetes Obes Metab. 2013. PMID: 23551925 Clinical Trial.
The aim was to investigate effects of liraglutide on appetite and energy intake in a randomized, placebo-controlled, double-blind, crossover study. ...Appetite ratings were assessed using visual analogue scales during a 5-h meal test. Energy and macronutrient intake …
The aim was to investigate effects of liraglutide on appetite and energy intake in a randomized, placebo-controlled, double-blind, cr …
Associations between postprandial insulin and blood glucose responses, appetite sensations and energy intake in normal weight and overweight individuals: a meta-analysis of test meal studies.
Flint A, Gregersen NT, Gluud LL, Møller BK, Raben A, Tetens I, Verdich C, Astrup A. Flint A, et al. Br J Nutr. 2007 Jul;98(1):17-25. doi: 10.1017/S000711450768297X. Epub 2007 May 25. Br J Nutr. 2007. PMID: 17524176 Review.
It is unclear whether postprandial blood glucose or insulin exerts a regulatory function in short-term appetite regulation in humans. ...
It is unclear whether postprandial blood glucose or insulin exerts a regulatory function in short-term appetite regulation in humans. …
Glycemic and insulinemic responses as determinants of appetite in humans.
Flint A, Møller BK, Raben A, Sloth B, Pedersen D, Tetens I, Holst JJ, Astrup A. Flint A, et al. Am J Clin Nutr. 2006 Dec;84(6):1365-73. doi: 10.1093/ajcn/84.6.1365. Am J Clin Nutr. 2006. PMID: 17158418 Clinical Trial.
DESIGN: The study was a randomized, crossover meal test including 28 healthy young men, each of whom tested 10 of 14 breakfast meals. ...Although no significant difference in EI(lunch) was observed between different breakfast conditions, a low breakfast EI was assoc …
DESIGN: The study was a randomized, crossover meal test including 28 healthy young men, each of whom tested 10 of 14 breakfast meals. …
A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women.
Krog-Mikkelsen I, Sloth B, Dimitrov D, Tetens I, Björck I, Flint A, Holst JJ, Astrup A, Elmståhl H, Raben A. Krog-Mikkelsen I, et al. J Nutr. 2011 Sep;141(9):1679-84. doi: 10.3945/jn.110.134627. Epub 2011 Jul 20. J Nutr. 2011. PMID: 21775528 Clinical Trial.
Two groups of a total of 29 healthy, overweight women (age: 30.5 ± 6.6 y; BMI: 27.6 ± 1.5 kg/m(2)) participated in the 10-wk intervention and a subsequent 4-h meal test. ...In conclusion, postprandial glycemia, insulinemia, and subjective appetite ratings after a
Two groups of a total of 29 healthy, overweight women (age: 30.5 ± 6.6 y; BMI: 27.6 ± 1.5 kg/m(2)) participated in the 10-wk interven …
Reproducibility and power of ad libitum energy intake assessed by repeated single meals.
Gregersen NT, Flint A, Bitz C, Blundell JE, Raben A, Astrup A. Gregersen NT, et al. Am J Clin Nutr. 2008 May;87(5):1277-81. doi: 10.1093/ajcn/87.5.1277. Am J Clin Nutr. 2008. PMID: 18469250 Clinical Trial.
A paired design with a study power of 0.8 requires 17 and 26 subjects, with and without prior diet standardization, respectively, to detect a difference of 500 kJ in EI. ...However, prior diet standardization exerts a significant effect on ad libitum E
A paired design with a study power of 0.8 requires 17 and 26 subjects, with and without prior diet standardization, respective
Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males.
Sloth B, Davidsen L, Holst JJ, Flint A, Astrup A. Sloth B, et al. Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E604-9. doi: 10.1152/ajpendo.00153.2007. Epub 2007 Jun 12. Am J Physiol Endocrinol Metab. 2007. PMID: 17566112 Clinical Trial.
Twenty-four males (BMI 27-40 kg/m(2)) were randomly assigned to two groups receiving sc injections of either PYY(1-36) or PYY(3-36) in a blinded, placebo-controlled, dose-escalating, cross-over study. ...The PYY(3-36) administrations caused a non-dose-dependent mobi …
Twenty-four males (BMI 27-40 kg/m(2)) were randomly assigned to two groups receiving sc injections of either PYY(1-36) or PYY(3-36) in a
Increased satiety after intake of a chocolate milk drink compared with a carbonated beverage, but no difference in subsequent ad libitum lunch intake.
Harper A, James A, Flint A, Astrup A. Harper A, et al. Br J Nutr. 2007 Mar;97(3):579-83. doi: 10.1017/S0007114507339846. Br J Nutr. 2007. PMID: 17313721 Clinical Trial.
The objective of the present study was to compare the effect on appetite and energy intake of a sugar-sweetened beverage (cola) and a chocolate milk drink, matched for energy content and volume. ...A drink of 500 ml cola or chocolate milk (900 kJ) was ingeste …
The objective of the present study was to compare the effect on appetite and energy intake of a sugar-sweetened beverage (cola) and …
Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.
Sloth B, Holst JJ, Flint A, Gregersen NT, Astrup A. Sloth B, et al. Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1062-8. doi: 10.1152/ajpendo.00450.2006. Epub 2006 Dec 5. Am J Physiol Endocrinol Metab. 2007. PMID: 17148749 Clinical Trial.
To compare effects of PYY(1-36) and PYY(3-36) on appetite, EI, EE, insulin, glucose and free fatty acids (FFA) concentrations, 12 lean and 12 obese males participated in a blinded, randomized, crossover study with 90-min infusions of saline, 0.8 pmol x kg(-1) x min(-1) PYY …
To compare effects of PYY(1-36) and PYY(3-36) on appetite, EI, EE, insulin, glucose and free fatty acids (FFA) concentrations, 12 lean and 1 …
No difference in body weight decrease between a low-glycemic-index and a high-glycemic-index diet but reduced LDL cholesterol after 10-wk ad libitum intake of the low-glycemic-index diet.
Sloth B, Krog-Mikkelsen I, Flint A, Tetens I, Björck I, Vinoy S, Elmståhl H, Astrup A, Lang V, Raben A. Sloth B, et al. Am J Clin Nutr. 2004 Aug;80(2):337-47. doi: 10.1093/ajcn/80.2.337. Am J Clin Nutr. 2004. PMID: 15277154 Clinical Trial.

However, a 10% decrease in LDL cholesterol (P < 0.05) and a tendency to a larger decrease in total cholesterol (P = 0.06) were observed with consumption of the LGI diet as compared with the HGI diet. ...However, it confirms previous findings of a be

However, a 10% decrease in LDL cholesterol (P < 0.05) and a tendency to a larger decrease in total cholesterol (P =

Effects of different dietary fat types on postprandial appetite and energy expenditure.
Flint A, Helt B, Raben A, Toubro S, Astrup A. Flint A, et al. Obes Res. 2003 Dec;11(12):1449-55. doi: 10.1038/oby.2003.194. Obes Res. 2003. PMID: 14694208 Clinical Trial.
RESEARCH METHODS AND PROCEDURES: Three test meals were randomly given in a cross-over design to 19 overweight (BMI: 26.8 +/- 0.4 kg/m2), young (25.2 +/- 0.7 years) men. ...EE was measured continuously in a respiration chamber, and appetite sensations were rated by v …
RESEARCH METHODS AND PROCEDURES: Three test meals were randomly given in a cross-over design to 19 overweight (BMI: 26.8 +/- 0.4 kg/m …
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