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Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain.
González S, Rangel-Barajas C, Peper M, Lorenzo R, Moreno E, Ciruela F, Borycz J, Ortiz J, Lluís C, Franco R, McCormick PJ, Volkow ND, Rubinstein M, Floran B, Ferré S. González S, et al. Among authors: floran b. Mol Psychiatry. 2012 Jun;17(6):650-62. doi: 10.1038/mp.2011.93. Epub 2011 Aug 16. Mol Psychiatry. 2012. PMID: 21844870 Free PMC article.
6-OHDA-induced hemiparkinsonism and chronic L-DOPA treatment increase dopamine D1-stimulated [(3)H]-GABA release and [(3)H]-cAMP production in substantia nigra pars reticulata of the rat.
Rangel-Barajas C, Silva I, García-Ramírez M, Sánchez-Lemus E, Floran L, Aceves J, Erlij D, Florán B. Rangel-Barajas C, et al. Among authors: floran l, floran b. Neuropharmacology. 2008 Oct;55(5):704-11. doi: 10.1016/j.neuropharm.2008.06.002. Epub 2008 Jun 7. Neuropharmacology. 2008. PMID: 18588904
Dopaminergic denervation switches dopamine D3 receptor signaling and disrupts its Ca(2+) dependent modulation by CaMKII and calmodulin in striatonigral projections of the rat.
Avalos-Fuentes A, Albarrán-Bravo S, Loya-Lopéz S, Cortés H, Recillas-Morales S, Magaña JJ, Paz-Bermúdez F, Rangel-Barajas C, Aceves J, Erlij D, Florán B. Avalos-Fuentes A, et al. Among authors: floran b. Neurobiol Dis. 2015 Feb;74:336-46. doi: 10.1016/j.nbd.2014.12.008. Epub 2014 Dec 14. Neurobiol Dis. 2015. PMID: 25517101
Dopamine Receptors and Neurodegeneration.
Rangel-Barajas C, Coronel I, Florán B. Rangel-Barajas C, et al. Among authors: floran b. Aging Dis. 2015 Oct 1;6(5):349-68. doi: 10.14336/AD.2015.0330. eCollection 2015 Sep. Aging Dis. 2015. PMID: 26425390 Free PMC article. Review.
Pharmacological targeting of G protein-coupled receptor heteromers.
Moreno E, Casajuana-Martin N, Coyle M, Campos BC, Galaj E, Del Torrent CL, Seyedian A, Rea W, Cai NS, Bonifazi A, Florán B, Xi ZX, Guitart X, Casadó V, Newman AH, Bishop C, Pardo L, Ferré S. Moreno E, et al. Among authors: floran b. Pharmacol Res. 2022 Nov;185:106476. doi: 10.1016/j.phrs.2022.106476. Epub 2022 Sep 28. Pharmacol Res. 2022. PMID: 36182040 Free PMC article.
Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants.
Ferré S, Belcher AM, Bonaventura J, Quiroz C, Sánchez-Soto M, Casadó-Anguera V, Cai NS, Moreno E, Boateng CA, Keck TM, Florán B, Earley CJ, Ciruela F, Casadó V, Rubinstein M, Volkow ND. Ferré S, et al. Among authors: floran b. Front Endocrinol (Lausanne). 2022 Sep 30;13:1014678. doi: 10.3389/fendo.2022.1014678. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36267569 Free PMC article. Review.
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