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Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.
Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, Arimondo PB, Miele E, Ferretti E, Gulino A, Diederich M, Cheng X, Mai A. Valente S, et al. Among authors: florean c. J Med Chem. 2014 Feb 13;57(3):701-13. doi: 10.1021/jm4012627. Epub 2014 Jan 15. J Med Chem. 2014. PMID: 24387159 Free PMC article.
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S. Zwergel C, et al. Among authors: florean c. Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8. Clin Epigenetics. 2019. PMID: 31060628 Free PMC article.
Correction: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S. Zwergel C, et al. Among authors: florean c. Clin Epigenetics. 2022 Sep 28;14(1):119. doi: 10.1186/s13148-022-01339-y. Clin Epigenetics. 2022. PMID: 36171618 Free PMC article. No abstract available.
Chromatin-modifying agents in anti-cancer therapy.
Seidel C, Florean C, Schnekenburger M, Dicato M, Diederich M. Seidel C, et al. Among authors: florean c. Biochimie. 2012 Nov;94(11):2264-79. doi: 10.1016/j.biochi.2012.05.012. Epub 2012 May 22. Biochimie. 2012. PMID: 22627380 Review.
Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.
Florean C, Schnekenburger M, Lee JY, Kim KR, Mazumder A, Song S, Kim JM, Grandjenette C, Kim JG, Yoon AY, Dicato M, Kim KW, Christov C, Han BW, Proksch P, Diederich M. Florean C, et al. Oncotarget. 2016 Apr 26;7(17):24027-49. doi: 10.18632/oncotarget.8210. Oncotarget. 2016. PMID: 27006469 Free PMC article.
24 results