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111 results

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Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome.
Giampietro L, Laghezza A, Cerchia C, Florio R, Recinella L, Capone F, Ammazzalorso A, Bruno I, De Filippis B, Fantacuzzi M, Ferrante C, Maccallini C, Tortorella P, Verginelli F, Brunetti L, Cama A, Amoroso R, Loiodice F, Lavecchia A. Giampietro L, et al. Among authors: florio r. ACS Med Chem Lett. 2019 Feb 25;10(4):545-551. doi: 10.1021/acsmedchemlett.8b00574. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996794 Free PMC article.
Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists.
Ammazzalorso A, Carrieri A, Verginelli F, Bruno I, Carbonara G, D'Angelo A, De Filippis B, Fantacuzzi M, Florio R, Fracchiolla G, Giampietro L, Giancristofaro A, Maccallini C, Cama A, Amoroso R. Ammazzalorso A, et al. Among authors: florio r. Eur J Med Chem. 2016 May 23;114:191-200. doi: 10.1016/j.ejmech.2016.02.064. Epub 2016 Feb 27. Eur J Med Chem. 2016. PMID: 26974385
Cytotoxic effect of a family of peroxisome proliferator-activated receptor antagonists in colorectal and pancreatic cancer cell lines.
Ammazzalorso A, De Lellis L, Florio R, Bruno I, De Filippis B, Fantacuzzi M, Giampietro L, Maccallini C, Perconti S, Verginelli F, Cama A, Amoroso R. Ammazzalorso A, et al. Among authors: florio r. Chem Biol Drug Des. 2017 Nov;90(5):1029-1035. doi: 10.1111/cbdd.13026. Epub 2017 Jul 19. Chem Biol Drug Des. 2017. PMID: 28544586
Effects of PPARα inhibition in head and neck paraganglioma cells.
Florio R, De Lellis L, di Giacomo V, Di Marcantonio MC, Cristiano L, Basile M, Verginelli F, Verzilli D, Ammazzalorso A, Prasad SC, Cataldi A, Sanna M, Cimini A, Mariani-Costantini R, Mincione G, Cama A. Florio R, et al. PLoS One. 2017 Jun 8;12(6):e0178995. doi: 10.1371/journal.pone.0178995. eCollection 2017. PLoS One. 2017. PMID: 28594934 Free PMC article.
Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib.
Verginelli F, Perconti S, Vespa S, Schiavi F, Prasad SC, Lanuti P, Cama A, Tramontana L, Esposito DL, Guarnieri S, Sheu A, Pantalone MR, Florio R, Morgano A, Rossi C, Bologna G, Marchisio M, D'Argenio A, Taschin E, Visone R, Opocher G, Veronese A, Paties CT, Rajasekhar VK, Söderberg-Nauclér C, Sanna M, Lotti LV, Mariani-Costantini R. Verginelli F, et al. Among authors: florio r. Acta Neuropathol. 2018 May;135(5):779-798. doi: 10.1007/s00401-017-1799-2. Epub 2018 Jan 5. Acta Neuropathol. 2018. PMID: 29305721 Free PMC article.
Correction to: Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib.
Verginelli F, Perconti S, Vespa S, Schiavi F, Prasad SC, Lanuti P, Cama A, Tramontana L, Esposito DL, Guarnieri S, Sheu A, Pantalone MR, Florio R, Morgano A, Rossi C, Bologna G, Marchisio M, D'Argenio A, Taschin E, Visone R, Opocher G, Veronese A, Paties CT, Rajasekhar VK, Söderberg-Nauclér C, Sanna M, Lotti LV, Mariani-Costantini R. Verginelli F, et al. Among authors: florio r. Acta Neuropathol. 2018 May;135(5):799. doi: 10.1007/s00401-018-1811-5. Acta Neuropathol. 2018. PMID: 29392445 Free PMC article.
Synthesis of novel benzothiazole amides: Evaluation of PPAR activity and anti-proliferative effects in paraganglioma, pancreatic and colorectal cancer cell lines.
Ammazzalorso A, De Lellis L, Florio R, Laghezza A, De Filippis B, Fantacuzzi M, Giampietro L, Maccallini C, Tortorella P, Veschi S, Loiodice F, Cama A, Amoroso R. Ammazzalorso A, et al. Among authors: florio r. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2302-2306. doi: 10.1016/j.bmcl.2019.06.020. Epub 2019 Jun 18. Bioorg Med Chem Lett. 2019. PMID: 31272790
111 results