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SARS-CoV-2 B cell receptor signatures in at-risk populations.
Flyak AI. Flyak AI. J Clin Invest. 2021 Jan 4;131(1):e144685. doi: 10.1172/JCI144685. J Clin Invest. 2021. PMID: 33216735 Free article.
Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells.
Kumar A, Hill TM, Gordy LE, Suryadevara N, Wu L, Flyak AI, Bezbradica JS, Van Kaer L, Joyce S. Kumar A, et al. Among authors: flyak ai. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17156-17165. doi: 10.1073/pnas.2001665117. Epub 2020 Jul 1. Proc Natl Acad Sci U S A. 2020. PMID: 32611812 Free PMC article.
An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein.
Flyak AI, Ruiz SE, Salas J, Rho S, Bailey JR, Bjorkman PJ. Flyak AI, et al. Elife. 2020 Mar 3;9:e53169. doi: 10.7554/eLife.53169. Elife. 2020. PMID: 32125272 Free PMC article.
Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatitis C virus clearance.
Kinchen VJ, Massaccesi G, Flyak AI, Mankowski MC, Colbert MD, Osburn WO, Ray SC, Cox AL, Crowe JE Jr, Bailey JR. Kinchen VJ, et al. Among authors: flyak ai. J Clin Invest. 2019 Aug 13;129(11):4786-4796. doi: 10.1172/JCI130720. J Clin Invest. 2019. PMID: 31408439 Free PMC article.
Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2.
Colbert MD, Flyak AI, Ogega CO, Kinchen VJ, Massaccesi G, Hernandez M, Davidson E, Doranz BJ, Cox AL, Crowe JE Jr, Bailey JR. Colbert MD, et al. Among authors: flyak ai. J Virol. 2019 Jun 28;93(14):e02070-18. doi: 10.1128/JVI.02070-18. Print 2019 Jul 15. J Virol. 2019. PMID: 31068427 Free PMC article.
Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection.
Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE Jr. Williamson LE, et al. Among authors: flyak ai. J Virol. 2019 Apr 3;93(8):e01439-18. doi: 10.1128/JVI.01439-18. Print 2019 Apr 15. J Virol. 2019. PMID: 30728263 Free PMC article.
Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection.
Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE Jr, Bjorkman PJ, Shaw GM, Bailey JR. Kinchen VJ, et al. Among authors: flyak ai. Cell Host Microbe. 2018 Nov 14;24(5):717-730.e5. doi: 10.1016/j.chom.2018.10.012. Cell Host Microbe. 2018. PMID: 30439341 Free PMC article.
HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE Jr, Bailey JR, Bjorkman PJ. Flyak AI, et al. Cell Host Microbe. 2018 Nov 14;24(5):703-716.e3. doi: 10.1016/j.chom.2018.10.009. Cell Host Microbe. 2018. PMID: 30439340 Free PMC article.
Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.
Ilinykh PA, Santos RI, Gunn BM, Kuzmina NA, Shen X, Huang K, Gilchuk P, Flyak AI, Younan P, Alter G, Crowe JE Jr, Bukreyev A. Ilinykh PA, et al. Among authors: flyak ai. PLoS Pathog. 2018 Aug 23;14(8):e1007204. doi: 10.1371/journal.ppat.1007204. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30138408 Free PMC article.
Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors.
Kuzmina NA, Younan P, Gilchuk P, Santos RI, Flyak AI, Ilinykh PA, Huang K, Lubaki NM, Ramanathan P, Crowe JE Jr, Bukreyev A. Kuzmina NA, et al. Among authors: flyak ai. Cell Rep. 2018 Aug 14;24(7):1802-1815.e5. doi: 10.1016/j.celrep.2018.07.035. Cell Rep. 2018. PMID: 30110637 Free PMC article.
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