Flynn MA - Search Results

1

Endothelin B receptors on human endothelial and smooth-muscle cells show equivalent binding pharmacology.

Flynn MA, Haleen SJ, Welch KM, Cheng XM, Reynolds EE. Flynn MA, et al. J Cardiovasc Pharmacol. 1998 Jul;32(1):106-16. doi: 10.1097/00005344-199807000-00017. J Cardiovasc Pharmacol. 1998. PMID: 9676729

2

Butenolide endothelin antagonists with improved aqueous solubility.

Patt WC, Cheng XM, Repine JT, Lee C, Reisdorph BR, Massa MA, Doherty AM, Welch KM, Bryant JW, Flynn MA, Walker DM, Schroeder RL, Haleen SJ, Keiser JA. Patt WC, et al. Among authors: flynn ma. J Med Chem. 1999 Jun 17;42(12):2162-8. doi: 10.1021/jm980504w. J Med Chem. 1999. PMID: 10377221

3

Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists.

Patt WC, Edmunds JJ, Repine JT, Berryman KA, Reisdorph BR, Lee C, Plummer MS, Shahripour A, Haleen SJ, Keiser JA, Flynn MA, Welch KM, Reynolds EE, Rubin R, Tobias B, Hallak H, Doherty AM. Patt WC, et al. Among authors: flynn ma. J Med Chem. 1997 Mar 28;40(7):1063-74. doi: 10.1021/jm9606507. J Med Chem. 1997. PMID: 9089328

4

Endothelin A receptor antagonism by PD 156707 does not reduce infarct size after coronary artery occlusion/reperfusion in pigs.

Mertz TE, McClanahan TB, Flynn MA, Juneau P, Reynolds EE, Hallak H, Bradford L, Gallagher KP. Mertz TE, et al. Among authors: flynn ma. J Pharmacol Exp Ther. 1996 Jul;278(1):42-9. J Pharmacol Exp Ther. 1996. PMID: 8764334

5

Endothelin and PDGF enhance arachidonic acid release and DNA synthesis in vascular smooth muscle cells.

Irons CE, Flynn MA, Mok LM, Reynolds EE. Irons CE, et al. Among authors: flynn ma. Am J Physiol. 1996 Jun;270(6 Pt 1):C1642-6. doi: 10.1152/ajpcell.1996.270.6.C1642. Am J Physiol. 1996. PMID: 8764146

6

Structure-activity relationships of a novel series of orally active nonpeptide ETA and ETA/B endothelin receptor-selective antagonists.

Doherty AM, Patt WC, Repine J, Edmunds JJ, Berryman KA, Reisdorph BR, Walker DM, Haleen SJ, Keiser JA, Flynn MA, et al. Doherty AM, et al. Among authors: flynn ma. J Cardiovasc Pharmacol. 1995;26 Suppl 3:S358-61. J Cardiovasc Pharmacol. 1995. PMID: 8587414

7

Truncated analogues of endothelin and sarafotoxin are selective for the ETB receptor subtype.

Heyl DL, Cody WL, He JX, Flynn MA, Welch KM, Reynolds EE, Doherty AM. Heyl DL, et al. Among authors: flynn ma. Pept Res. 1993 Sep-Oct;6(5):238-41. Pept Res. 1993. PMID: 8257799

8

ETA and ETB receptors coexist on rabbit pulmonary artery vascular smooth muscle mediating contraction.

LaDouceur DM, Flynn MA, Keiser JA, Reynolds E, Haleen SJ. LaDouceur DM, et al. Among authors: flynn ma. Biochem Biophys Res Commun. 1993 Oct 15;196(1):209-15. doi: 10.1006/bbrc.1993.2236. Biochem Biophys Res Commun. 1993. PMID: 8216294

9

Pharmacological characterization of PD 156707, an orally active ETA receptor antagonist.

Reynolds EE, Keiser JA, Haleen SJ, Walker DM, Olszewski B, Schroeder RL, Taylor DG, Hwang O, Welch KM, Flynn MA, et al. Reynolds EE, et al. Among authors: flynn ma. J Pharmacol Exp Ther. 1995 Jun;273(3):1410-7. J Pharmacol Exp Ther. 1995. PMID: 7791115

10

Pharmacological differences between rat and human endothelin B receptors.

Reynolds EE, Hwang O, Flynn MA, Welch KM, Cody WL, Steinbaugh B, He JX, Chung FZ, Doherty AM. Reynolds EE, et al. Among authors: flynn ma. Biochem Biophys Res Commun. 1995 Apr 17;209(2):506-12. doi: 10.1006/bbrc.1995.1530. Biochem Biophys Res Commun. 1995. PMID: 7733918

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