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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1960 1
1961 1
1962 4
1963 13
1964 19
1965 33
1966 43
1967 49
1968 55
1969 70
1970 90
1971 88
1972 106
1973 112
1974 107
1975 189
1976 181
1977 157
1978 152
1979 155
1980 171
1981 166
1982 169
1983 211
1984 170
1985 204
1986 215
1987 226
1988 198
1989 258
1990 227
1991 221
1992 283
1993 298
1994 276
1995 324
1996 332
1997 388
1998 453
1999 514
2000 560
2001 594
2002 662
2003 777
2004 854
2005 905
2006 880
2007 1032
2008 1054
2009 995
2010 1096
2011 1174
2012 1269
2013 1279
2014 1321
2015 1341
2016 1298
2017 1349
2018 1356
2019 1398
2020 1459
2021 1435
2022 1311
2023 141
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29,472 results
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Page 1
Nutritional role of folate.
Ebara S. Ebara S. Congenit Anom (Kyoto). 2017 Sep;57(5):138-141. doi: 10.1111/cga.12233. Epub 2017 Jul 25. Congenit Anom (Kyoto). 2017. PMID: 28603928 Review.
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. ...This paper describes the basic features and nutritional role of folate....
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. ...This paper describes t …
The association of folate and depression: A meta-analysis.
Bender A, Hagan KE, Kingston N. Bender A, et al. J Psychiatr Res. 2017 Dec;95:9-18. doi: 10.1016/j.jpsychires.2017.07.019. Epub 2017 Jul 22. J Psychiatr Res. 2017. PMID: 28759846 Review.
METHODS: Meta-analytic procedures were conducted in accordance with PRISMA guidelines. Studies evaluating folate levels in individuals with and without depression via red blood cell folate, serum folate, or dietary intake of folate methods were identif …
METHODS: Meta-analytic procedures were conducted in accordance with PRISMA guidelines. Studies evaluating folate levels in individual …
Genetic polymorphisms and folate status.
Hiraoka M, Kagawa Y. Hiraoka M, et al. Congenit Anom (Kyoto). 2017 Sep;57(5):142-149. doi: 10.1111/cga.12232. Epub 2017 Jul 20. Congenit Anom (Kyoto). 2017. PMID: 28598562 Free PMC article. Review.
In the folate cycle and homocysteine metabolism, folate, vitamin B12, vitamin B6, and vitamin B2 are important cofactors. ...Serum folate and total Hcy (tHcy) levels are influenced by folate intake and genetic polymorphisms in 5,10-methylenetertahydrof …
In the folate cycle and homocysteine metabolism, folate, vitamin B12, vitamin B6, and vitamin B2 are important cofactors. ...S …
Laboratory assessment of folate (vitamin B9) status.
Sobczyńska-Malefora A, Harrington DJ. Sobczyńska-Malefora A, et al. J Clin Pathol. 2018 Nov;71(11):949-956. doi: 10.1136/jclinpath-2018-205048. Epub 2018 Sep 18. J Clin Pathol. 2018. PMID: 30228213 Review.
Folate deficiency and excess has also been implicated in some cancers. ...The analysis of folate in red cells is also commonly performed. Since the folate content of red cells is fixed during erythropoiesis, this marker is indicative of folate status o
Folate deficiency and excess has also been implicated in some cancers. ...The analysis of folate in red cells is also commonly
Cerebral folate deficiency: Analytical tests and differential diagnosis.
Pope S, Artuch R, Heales S, Rahman S. Pope S, et al. J Inherit Metab Dis. 2019 Jul;42(4):655-672. doi: 10.1002/jimd.12092. Epub 2019 May 2. J Inherit Metab Dis. 2019. PMID: 30916789 Review.
Cerebral folate deficiency is typically defined as a deficiency of the major folate species 5-methyltetrahydrofolate in the cerebrospinal fluid (CSF) in the presence of normal peripheral total folate levels. ...Known defects of folate transport are def …
Cerebral folate deficiency is typically defined as a deficiency of the major folate species 5-methyltetrahydrofolate in the ce …
The Role of Folate and MTHFR Polymorphisms in the Treatment of Depression.
Stengler M. Stengler M. Altern Ther Health Med. 2021 Mar;27(2):53-57. Altern Ther Health Med. 2021. PMID: 32827402
For those people that do not benefit from the standard therapy or prefer non-pharmacologic therapy, folate supplementation may be an option. Folate is normally acquired through the diet and folate deficiency is associated with depression. ...Studies involving …
For those people that do not benefit from the standard therapy or prefer non-pharmacologic therapy, folate supplementation may be an …
Methionine synthase is essential for cancer cell proliferation in physiological folate environments.
Sullivan MR, Darnell AM, Reilly MF, Kunchok T, Joesch-Cohen L, Rosenberg D, Ali A, Rees MG, Roth JA, Lewis CA, Vander Heiden MG. Sullivan MR, et al. Nat Metab. 2021 Nov;3(11):1500-1511. doi: 10.1038/s42255-021-00486-5. Epub 2021 Nov 18. Nat Metab. 2021. PMID: 34799701 Free PMC article.
Folate metabolism can be an effective target for cancer treatment. However, standard cell culture conditions utilize folic acid, a non-physiological folate source for most tissues. We find that the enzyme that couples folate and methionine metabolic cycles, m
Folate metabolism can be an effective target for cancer treatment. However, standard cell culture conditions utilize folic acid, a no
66/67/68Ga-γ-Deferoxamine-folate.
Leung K. Leung K. 2006 Sep 14 [updated 2011 Jan 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2006 Sep 14 [updated 2011 Jan 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641297 Free Books & Documents. Review.
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate (Michaelis constant (K(m)) = 1-5 muM). ...Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate and …
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate
99mTc-1,4,7-Tris(carboxymethyl)-10-(4-aminoethyl)-1,4,7,10-tetraazacyclododecane-Folate.
Leung K. Leung K. 2012 Nov 22 [updated 2013 Jan 31]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Nov 22 [updated 2013 Jan 31]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23390668 Free Books & Documents. Review.
Breast, colorectal, renal, and lung carcinomas also overexpressed the high-affinity folate receptor but to a lesser frequency (20%-50%). Several (99m)Tc-based folate conjugates have been developed for single-photon emission computed tomography (SPECT) imaging of …
Breast, colorectal, renal, and lung carcinomas also overexpressed the high-affinity folate receptor but to a lesser frequency (20%-50 …
67Ga-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-3-{2-[2-(3-amino-propoxy)-ethoxy]-ethoxy}-propylamine-γ-folate.
Leung K. Leung K. 2011 Feb 14 [updated 2011 May 26]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2011 Feb 14 [updated 2011 May 26]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21634077 Free Books & Documents. Review.
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate (Michaelis constant (K(m)) = 1-5 muM). ...Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate, and …
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate
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