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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
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1961 1
1962 4
1963 13
1964 19
1965 33
1966 43
1967 49
1968 55
1969 70
1970 90
1971 88
1972 106
1973 112
1974 107
1975 189
1976 181
1977 157
1978 152
1979 155
1980 171
1981 166
1982 169
1983 211
1984 170
1985 204
1986 215
1987 226
1988 198
1989 258
1990 227
1991 221
1992 283
1993 303
1994 276
1995 324
1996 332
1997 388
1998 454
1999 514
2000 560
2001 594
2002 662
2003 777
2004 854
2005 905
2006 880
2007 1032
2008 1054
2009 995
2010 1096
2011 1174
2012 1270
2013 1279
2014 1322
2015 1343
2016 1297
2017 1347
2018 1356
2019 1397
2020 1458
2021 1439
2022 1331
2023 1399
2024 1405
2025 1668
2026 1084

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34,353 results

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Page 1
Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder.
Frye RE, Rossignol DA, Scahill L, McDougle CJ, Huberman H, Quadros EV. Frye RE, et al. Semin Pediatr Neurol. 2020 Oct;35:100835. doi: 10.1016/j.spen.2020.100835. Epub 2020 Jun 25. Semin Pediatr Neurol. 2020. PMID: 32892962 Free PMC article. Review.
One of these abnormalities involves a partial blockage in the ability of folate to be transported into the brain utilizing the primary transport mechanism, the folate receptor alpha. ...Most significantly, case-series, open-label, and single and double-blind placebo …
One of these abnormalities involves a partial blockage in the ability of folate to be transported into the brain utilizing the primar …
Cerebral Folate Deficiency Syndrome: Early Diagnosis, Intervention and Treatment Strategies.
Ramaekers VT, Quadros EV. Ramaekers VT, et al. Nutrients. 2022 Jul 28;14(15):3096. doi: 10.3390/nu14153096. Nutrients. 2022. PMID: 35956272 Free PMC article. Review.
Cerebral folate deficiency syndrome (CFDS) is defined as any neuropsychiatric or developmental disorder characterized by decreased CSF folate levels in the presence of normal folate status outside the nervous system. The specific clinical profile appears to b …
Cerebral folate deficiency syndrome (CFDS) is defined as any neuropsychiatric or developmental disorder characterized by decreased CS …
(99m)Tc-1,4,7-Tris(carboxymethyl)-10-(4-aminoethyl)-1,4,7,10-tetraazacyclododecane-Folate.
Leung K. Leung K. 2012 Nov 22 [updated 2013 Jan 31]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Nov 22 [updated 2013 Jan 31]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23390668 Free Books & Documents. Review.
Breast, colorectal, renal, and lung carcinomas also overexpressed the high-affinity folate receptor but to a lesser frequency (20%-50%). Several (99m)Tc-based folate conjugates have been developed for single-photon emission computed tomography (SPECT) imaging of …
Breast, colorectal, renal, and lung carcinomas also overexpressed the high-affinity folate receptor but to a lesser frequency (20%-50 …
(66/67/68)Ga-gamma-Deferoxamine-folate.
Leung K. Leung K. 2006 Sep 14 [updated 2011 Jan 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2006 Sep 14 [updated 2011 Jan 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641297 Free Books & Documents. Review.
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate (Michaelis constant (K(m)) = 1-5 muM). ...Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate and …
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate …
(67/68)Ga-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-1,2-diaminoethane-gamma-folate.
Leung K. Leung K. 2011 Feb 14 [updated 2011 May 26]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2011 Feb 14 [updated 2011 May 26]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21634076 Free Books & Documents. Review.
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate (Michaelis constant (K(m)) = 1-5 muM). ...Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate, and …
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate …
[(18)F]alpha/gamma-Fluorobenzylamine-folate.
Leung K. Leung K. 2006 Jul 12 [updated 2006 Aug 7]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2006 Jul 12 [updated 2006 Aug 7]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641227 Free Books & Documents. Review.
Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate and (68/67/66)Ga-DF-folate) have been studied in tumor imaging (4-7). Bettio et al. (8) reported a synthesis of 18F-labeled folate by a reaction of [(18)F]4-fluorobenzylamin …
Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate and (68/67/66)Ga-DF-folate) have been st …
Nutritional role of folate.
Ebara S. Ebara S. Congenit Anom (Kyoto). 2017 Sep;57(5):138-141. doi: 10.1111/cga.12233. Epub 2017 Jul 25. Congenit Anom (Kyoto). 2017. PMID: 28603928 Review.
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. To reduce the risk of NTDs, supplementation with folic acid (a synthetic form of folate) during the periconceptional period has also been recommended. This pa …
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. To reduce the risk of NTD …
Medicines associated with folate-homocysteine-methionine pathway disruption.
Vidmar M, Grželj J, Mlinarič-Raščan I, Geršak K, Dolenc MS. Vidmar M, et al. Arch Toxicol. 2019 Feb;93(2):227-251. doi: 10.1007/s00204-018-2364-z. Epub 2018 Nov 29. Arch Toxicol. 2019. PMID: 30499019 Review.
Adequate folate levels are essential in women of childbearing age and in pregnant women, and folate deficiency is associated with several congenital malformations. Low folate levels can be caused by dietary deficiencies, a genetic predisposition or treatment …
Adequate folate levels are essential in women of childbearing age and in pregnant women, and folate deficiency is associated w …
Folate metabolism and requirements.
Bailey LB, Gregory JF 3rd. Bailey LB, et al. J Nutr. 1999 Apr;129(4):779-82. doi: 10.1093/jn/129.4.779. J Nutr. 1999. PMID: 10203550 Review.
Folate-requiring metabolic processes are influenced by folate intake, intake of other essential nutrients, including vitamins B-12 and B-6, and at least one common genetic polymorphism. Estimates of folate requirements have been based on intakes associated wi …
Folate-requiring metabolic processes are influenced by folate intake, intake of other essential nutrients, including vitamins …
Folate-producing bifidobacteria: metabolism, genetics, and relevance.
D'Aimmo MR, Satti M, Scarafile D, Modesto M, Pascarelli S, Biagini SA, Luiselli D, Mattarelli P, Andlid T. D'Aimmo MR, et al. Microbiome Res Rep. 2023 Dec 12;3(1):11. doi: 10.20517/mrr.2023.59. eCollection 2024. Microbiome Res Rep. 2023. PMID: 38455078 Free PMC article. Review.
Folate delivers 1C units, such as methyl and formyl, between reactants. Plants, algae, fungi, and many bacteria can naturally produce folate, whereas animals, including humans, must obtain folate from external sources. ...Biotechnologies based on folate …
Folate delivers 1C units, such as methyl and formyl, between reactants. Plants, algae, fungi, and many bacteria can naturally produce …
34,353 results
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