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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1960 1
1961 1
1962 4
1963 13
1964 19
1965 33
1966 43
1967 49
1968 55
1969 70
1970 90
1971 88
1972 106
1973 112
1974 107
1975 189
1976 181
1977 157
1978 152
1979 155
1980 171
1981 166
1982 169
1983 211
1984 170
1985 204
1986 215
1987 226
1988 198
1989 258
1990 227
1991 221
1992 283
1993 300
1994 276
1995 324
1996 332
1997 388
1998 453
1999 514
2000 560
2001 594
2002 662
2003 777
2004 854
2005 905
2006 880
2007 1032
2008 1054
2009 995
2010 1096
2011 1174
2012 1269
2013 1279
2014 1321
2015 1341
2016 1298
2017 1349
2018 1356
2019 1397
2020 1457
2021 1437
2022 1334
2023 1396
2024 1072

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31,576 results

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Page 1
Nutritional role of folate.
Ebara S. Ebara S. Congenit Anom (Kyoto). 2017 Sep;57(5):138-141. doi: 10.1111/cga.12233. Epub 2017 Jul 25. Congenit Anom (Kyoto). 2017. PMID: 28603928 Review.
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. To reduce the risk of NTDs, supplementation with folic acid (a synthetic form of folate) during the periconceptional period has also been recommended. This pa …
It has also been recommended that folate be consumed in the diet to promote the maintenance of good health. To reduce the risk of NTD …
Methionine synthase is essential for cancer cell proliferation in physiological folate environments.
Sullivan MR, Darnell AM, Reilly MF, Kunchok T, Joesch-Cohen L, Rosenberg D, Ali A, Rees MG, Roth JA, Lewis CA, Vander Heiden MG. Sullivan MR, et al. Nat Metab. 2021 Nov;3(11):1500-1511. doi: 10.1038/s42255-021-00486-5. Epub 2021 Nov 18. Nat Metab. 2021. PMID: 34799701 Free PMC article.
Folate metabolism can be an effective target for cancer treatment. However, standard cell culture conditions utilize folic acid, a non-physiological folate source for most tissues. We find that the enzyme that couples folate and methionine metabolic cycles, m …
Folate metabolism can be an effective target for cancer treatment. However, standard cell culture conditions utilize folic acid, a no …
Human folate bioavailability.
Ohrvik VE, Witthoft CM. Ohrvik VE, et al. Nutrients. 2011 Apr;3(4):475-90. doi: 10.3390/nu3040475. Epub 2011 Apr 18. Nutrients. 2011. PMID: 22254106 Free PMC article. Review.
Other countries have decided against fortification due to the ambiguous role of synthetic folic acid regarding promotion of subclinical cancers and other adverse health effects. This paper reviews recent studies on folate bioavailability after intervention with folate …
Other countries have decided against fortification due to the ambiguous role of synthetic folic acid regarding promotion of subclinical canc …
Genetic polymorphisms and folate status.
Hiraoka M, Kagawa Y. Hiraoka M, et al. Congenit Anom (Kyoto). 2017 Sep;57(5):142-149. doi: 10.1111/cga.12232. Epub 2017 Jul 20. Congenit Anom (Kyoto). 2017. PMID: 28598562 Free PMC article. Review.
In the folate cycle and homocysteine metabolism, folate, vitamin B12, vitamin B6, and vitamin B2 are important cofactors. ...Serum folate and total Hcy (tHcy) levels are influenced by folate intake and genetic polymorphisms in 5,10-methylenetertahydrof …
In the folate cycle and homocysteine metabolism, folate, vitamin B12, vitamin B6, and vitamin B2 are important cofactors. ...S …
Medicines associated with folate-homocysteine-methionine pathway disruption.
Vidmar M, Grželj J, Mlinarič-Raščan I, Geršak K, Dolenc MS. Vidmar M, et al. Arch Toxicol. 2019 Feb;93(2):227-251. doi: 10.1007/s00204-018-2364-z. Epub 2018 Nov 29. Arch Toxicol. 2019. PMID: 30499019 Review.
Adequate folate levels are essential in women of childbearing age and in pregnant women, and folate deficiency is associated with several congenital malformations. Low folate levels can be caused by dietary deficiencies, a genetic predisposition or treatment …
Adequate folate levels are essential in women of childbearing age and in pregnant women, and folate deficiency is associated w …
Folate and phototherapy: What should we inform our patients?
Zhang M, Goyert G, Lim HW. Zhang M, et al. J Am Acad Dermatol. 2017 Nov;77(5):958-964. doi: 10.1016/j.jaad.2016.10.016. J Am Acad Dermatol. 2017. PMID: 29029903 Review.
BACKGROUND: Ultraviolet (UV) degradation of folate has been studied in vitro and in vivo, but comprehensive reviews of the subject and recommendations for supplementing folate are lacking, especially for women of childbearing age, in whom decreases in folate …
BACKGROUND: Ultraviolet (UV) degradation of folate has been studied in vitro and in vivo, but comprehensive reviews of the subject an …
The association of folate and depression: A meta-analysis.
Bender A, Hagan KE, Kingston N. Bender A, et al. J Psychiatr Res. 2017 Dec;95:9-18. doi: 10.1016/j.jpsychires.2017.07.019. Epub 2017 Jul 22. J Psychiatr Res. 2017. PMID: 28759846 Review.
Studies evaluating folate levels in individuals with and without depression via red blood cell folate, serum folate, or dietary intake of folate methods were identified via PsycINFO and PubMed. ...Study heterogeneity was high (I(2) = 84.88%), and neith …
Studies evaluating folate levels in individuals with and without depression via red blood cell folate, serum folate, or …
(66/67/68)Ga-gamma-Deferoxamine-folate.
Leung K. Leung K. 2006 Sep 14 [updated 2011 Jan 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2006 Sep 14 [updated 2011 Jan 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641297 Free Books & Documents. Review.
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate (Michaelis constant (K(m)) = 1-5 muM). ...Several folate-based conjugates ((111)In-DTPA-folate, (99m)Tc-EC-folate and …
The primary pathway for entry of folate into cells is through the facilitated transporter, which has a low affinity for folate …
Role of Folate in Liver Diseases.
Yang M, Wang D, Wang X, Mei J, Gong Q. Yang M, et al. Nutrients. 2024 Jun 14;16(12):1872. doi: 10.3390/nu16121872. Nutrients. 2024. PMID: 38931227 Free PMC article. Review.
Folate deficiency due to low dietary intake, poor absorption of folate, and alterations in folate metabolism due to genetic defects or drug interactions significantly increases the risk of diseases such as neural tube defects, cardiovascular disease, cancer, …
Folate deficiency due to low dietary intake, poor absorption of folate, and alterations in folate metabolism due to gen …
(99m)Tc-1,4,7-Tris(carboxymethyl)-10-(4-aminoethyl)-1,4,7,10-tetraazacyclododecane-Folate.
Leung K. Leung K. 2012 Nov 22 [updated 2013 Jan 31]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Nov 22 [updated 2013 Jan 31]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23390668 Free Books & Documents. Review.
Breast, colorectal, renal, and lung carcinomas also overexpressed the high-affinity folate receptor but to a lesser frequency (20%-50%). Several (99m)Tc-based folate conjugates have been developed for single-photon emission computed tomography (SPECT) imaging of …
Breast, colorectal, renal, and lung carcinomas also overexpressed the high-affinity folate receptor but to a lesser frequency (20%-50 …
31,576 results
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