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Page 1
Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.
Fontanals-Cirera B, Hasson D, Vardabasso C, Di Micco R, Agrawal P, Chowdhury A, Gantz M, de Pablos-Aragoneses A, Morgenstern A, Wu P, Filipescu D, Valle-Garcia D, Darvishian F, Roe JS, Davies MA, Vakoc CR, Hernando E, Bernstein E. Fontanals-Cirera B, et al. Mol Cell. 2017 Nov 16;68(4):731-744.e9. doi: 10.1016/j.molcel.2017.11.004. Mol Cell. 2017. PMID: 29149598 Free PMC article.
BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy.
Segura MF, Fontanals-Cirera B, Gaziel-Sovran A, Guijarro MV, Hanniford D, Zhang G, González-Gomez P, Morante M, Jubierre L, Zhang W, Darvishian F, Ohlmeyer M, Osman I, Zhou MM, Hernando E. Segura MF, et al. Among authors: fontanals cirera b. Cancer Res. 2013 Oct 15;73(20):6264-76. doi: 10.1158/0008-5472.CAN-13-0122-T. Epub 2013 Aug 15. Cancer Res. 2013. PMID: 23950209 Free PMC article.
Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes.
Di Micco R, Fontanals-Cirera B, Low V, Ntziachristos P, Yuen SK, Lovell CD, Dolgalev I, Yonekubo Y, Zhang G, Rusinova E, Gerona-Navarro G, Cañamero M, Ohlmeyer M, Aifantis I, Zhou MM, Tsirigos A, Hernando E. Di Micco R, et al. Among authors: fontanals cirera b. Cell Rep. 2014 Oct 9;9(1):234-247. doi: 10.1016/j.celrep.2014.08.055. Epub 2014 Sep 26. Cell Rep. 2014. PMID: 25263550 Free PMC article.
Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma.
Vardabasso C, Gaspar-Maia A, Hasson D, Pünzeler S, Valle-Garcia D, Straub T, Keilhauer EC, Strub T, Dong J, Panda T, Chung CY, Yao JL, Singh R, Segura MF, Fontanals-Cirera B, Verma A, Mann M, Hernando E, Hake SB, Bernstein E. Vardabasso C, et al. Among authors: fontanals cirera b. Mol Cell. 2015 Jul 2;59(1):75-88. doi: 10.1016/j.molcel.2015.05.009. Epub 2015 Jun 4. Mol Cell. 2015. PMID: 26051178 Free PMC article.
A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.
Agrawal P, Fontanals-Cirera B, Sokolova E, Jacob S, Vaiana CA, Argibay D, Davalos V, McDermott M, Nayak S, Darvishian F, Castillo M, Ueberheide B, Osman I, Fenyö D, Mahal LK, Hernando E. Agrawal P, et al. Among authors: fontanals cirera b. Cancer Cell. 2017 Jun 12;31(6):804-819.e7. doi: 10.1016/j.ccell.2017.05.007. Cancer Cell. 2017. PMID: 28609658 Free PMC article.
Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability.
Santamaría PG, Floristán A, Fontanals-Cirera B, Vázquez-Naharro A, Santos V, Morales S, Yuste L, Peinado H, García-Gómez A, Portillo F, Hernando E, Cano A. Santamaría PG, et al. Among authors: fontanals cirera b. Cell Death Differ. 2018 May;25(5):935-950. doi: 10.1038/s41418-017-0030-2. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229995 Free PMC article.
An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma.
Davalos V, Lovell CD, Von Itter R, Dolgalev I, Agrawal P, Baptiste G, Kahler DJ, Sokolova E, Moran S, Piqué L, Vega-Saenz de Miera E, Fontanals-Cirera B, Karz A, Tsirigos A, Yun C, Darvishian F, Etchevers HC, Osman I, Esteller M, Schober M, Hernando E. Davalos V, et al. Among authors: fontanals cirera b. Nat Commun. 2023 Apr 4;14(1):1867. doi: 10.1038/s41467-023-36967-2. Nat Commun. 2023. PMID: 37015919 Free PMC article.