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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1964 2
1966 1
1967 1
1971 2
1972 3
1973 1
1974 1
1975 2
1976 2
1978 1
1979 1
1980 2
1981 2
1982 3
1983 1
1984 1
1985 3
1986 2
1987 4
1988 4
1989 10
1990 6
1991 11
1992 13
1993 13
1994 12
1995 8
1996 16
1997 21
1998 20
1999 28
2000 35
2001 40
2002 62
2003 78
2004 65
2005 81
2006 86
2007 132
2008 121
2009 132
2010 170
2011 167
2012 217
2013 222
2014 360
2015 445
2016 508
2017 654
2018 853
2019 966
2020 1236
2021 1462
2022 1602
2023 1584
2024 1737
2025 1993
2026 729

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13,722 results

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Page 1
Gut microbiota modulation of chemotherapy efficacy and toxicity.
Alexander JL, Wilson ID, Teare J, Marchesi JR, Nicholson JK, Kinross JM. Alexander JL, et al. Nat Rev Gastroenterol Hepatol. 2017 Jun;14(6):356-365. doi: 10.1038/nrgastro.2017.20. Epub 2017 Mar 8. Nat Rev Gastroenterol Hepatol. 2017. PMID: 28270698 Free article. Review.
Metabolic modulation of tumours with engineered bacteria for immunotherapy.
Canale FP, Basso C, Antonini G, Perotti M, Li N, Sokolovska A, Neumann J, James MJ, Geiger S, Jin W, Theurillat JP, West KA, Leventhal DS, Lora JM, Sallusto F, Geiger R. Canale FP, et al. Nature. 2021 Oct;598(7882):662-666. doi: 10.1038/s41586-021-04003-2. Epub 2021 Oct 6. Nature. 2021. PMID: 34616044
Here we used a synthetic biology approach to develop an engineered probiotic Escherichia coli Nissle 1917 strain that colonizes tumours and continuously converts ammonia, a metabolic waste product that accumulates in tumours(6), to L-arginine. ...The anti-tumour effect of …
Here we used a synthetic biology approach to develop an engineered probiotic Escherichia coli Nissle 1917 strain that colonizes tumou …
Multidimensional control of therapeutic human cell function with synthetic gene circuits.
Li HS, Israni DV, Gagnon KA, Gan KA, Raymond MH, Sander JD, Roybal KT, Joung JK, Wong WW, Khalil AS. Li HS, et al. Science. 2022 Dec 16;378(6625):1227-1234. doi: 10.1126/science.ade0156. Epub 2022 Dec 15. Science. 2022. PMID: 36520914 Free PMC article.
Here, we developed synthetic zinc finger transcription regulators (synZiFTRs), which are compact and based largely on human-derived proteins. As a proof of principle, we engineered gene switches and circuits that allow precise, user-defined control over therapeutically rel …
Here, we developed synthetic zinc finger transcription regulators (synZiFTRs), which are compact and based largely on human-derived proteins …
Preoperative Management of Surgical Patients Using Dietary Supplements: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement.
Cummings KC 3rd, Keshock M, Ganesh R, Sigmund A, Kashiwagi D, Devarajan J, Grant PJ, Urman RD, Mauck KF. Cummings KC 3rd, et al. Mayo Clin Proc. 2021 May;96(5):1342-1355. doi: 10.1016/j.mayocp.2020.08.016. Epub 2021 Mar 16. Mayo Clin Proc. 2021. PMID: 33741131
We have made our recommendations to discontinue or continue a dietary supplement based on the principle that without a demonstrated benefit, or with a demonstrated lack of harm, there is little downside in temporarily discontinuing an herbal supplement before surgery. Disc …
We have made our recommendations to discontinue or continue a dietary supplement based on the principle that without a demonstrated benefit, …
Engineering Digestion: Multiscale Processes of Food Digestion.
Bornhorst GM, Gouseti O, Wickham MS, Bakalis S. Bornhorst GM, et al. J Food Sci. 2016 Mar;81(3):R534-43. doi: 10.1111/1750-3841.13216. Epub 2016 Jan 22. J Food Sci. 2016. PMID: 26799793 Free article. Review.
Food digestion is a complex, multiscale process that has recently become of interest to the food industry due to the developing links between food and health or disease. ...To facilitate optimized development of functional food products, a multiscale, …
Food digestion is a complex, multiscale process that has recently become of interest to the food industry due to the developin …
Reprogramming extracellular vesicles with engineered proteins.
Shi X, Cheng Q, Zhang Y. Shi X, et al. Methods. 2020 May 1;177:95-102. doi: 10.1016/j.ymeth.2019.09.017. Epub 2019 Sep 27. Methods. 2020. PMID: 31568822 Review.
Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attra …
Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including ca …
Novel Targets and Therapeutic Strategies for Promoting Organ Repair and Regeneration.
Muruganandan S, Wigerius M. Muruganandan S, et al. Biomolecules. 2020 May 12;10(5):749. doi: 10.3390/biom10050749. Biomolecules. 2020. PMID: 32408488 Free PMC article.
Several new treatment options, including stem cell treatments and tissue-engineered substitutes for certain indications, have been approved by Food and Drug Administration (FDA) and are currently available. ...
Several new treatment options, including stem cell treatments and tissue-engineered substitutes for certain indications, have been ap …
Engineered probiotic-derived indole-3-propionic acid inhibits ubiquitination via AHR signaling to treat postmenopausal osteoporosis.
Qiu X, Wu L, Jiang F, Shan H, Sheng L, Tian B, Wang H, Cui H, Tao L, Wu C, Yao Y, Wang C, Zhou X, Zhang Y, Bai J. Qiu X, et al. Gut Microbes. 2026 Dec 31;18(1):2612620. doi: 10.1080/19490976.2025.2612620. Epub 2026 Jan 8. Gut Microbes. 2026. PMID: 41508814 Free PMC article.
Intraperitoneal IPA (20 mg/kg, 3 per week for 8 weeks) increased the trabecular bone mineral density (Tb.BMD) by ~68% versus OVX controls, whereas engineered Clostridium sporogenes that enhances IPA biosynthesis led to an even greater increase of ~118%. Together, these fi …
Intraperitoneal IPA (20 mg/kg, 3 per week for 8 weeks) increased the trabecular bone mineral density (Tb.BMD) by ~68% versus OVX controls, …
Bioreactors for succinic acid production processes.
Ferone M, Raganati F, Olivieri G, Marzocchella A. Ferone M, et al. Crit Rev Biotechnol. 2019 Jun;39(4):571-586. doi: 10.1080/07388551.2019.1592105. Epub 2019 Mar 31. Crit Rev Biotechnol. 2019. PMID: 30931643 Review.
Fermentation SA production from renewable carbohydrate feedstocks can have the economic and sustainability potential to replace petroleum-based production in the future, not only for existing markets, but also for new larger volume markets. Design and operation of bio-reac …
Fermentation SA production from renewable carbohydrate feedstocks can have the economic and sustainability potential to replace petroleum-ba …
Thermotolerant yeasts promoting climate-resilient bioproduction.
Shirvani R, Babaei M, Baladi M, Steiger MG, Barshan-Tashnizi M. Shirvani R, et al. FEMS Yeast Res. 2025 Jan 30;25:foaf047. doi: 10.1093/femsyr/foaf047. FEMS Yeast Res. 2025. PMID: 40928471 Free PMC article. Review.
The growing challenges posed by global warming and the demand for sustainable food and feed resources underscore the need for robust microbial platforms in bioprocessing. ...The cellular and molecular mechanisms underlying thermotolerance are also reviewed, including heat …
The growing challenges posed by global warming and the demand for sustainable food and feed resources underscore the need for robust …
13,722 results
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