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An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.
Findlay A, Turner C, Schilter H, Deodhar M, Zhou W, Perryman L, Foot J, Zahoor A, Yao Y, Hamilton R, Brock M, Raso C, Stolp J, Galati M, Hamprecht D, Charlton B, Jarolimek W. Findlay A, et al. Clin Transl Med. 2021 Nov;11(11):e572. doi: 10.1002/ctm2.572. Clin Transl Med. 2021. PMID: 34841699 Free PMC article. No abstract available.
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Chang J, Lucas MC, Leonte LE, Garcia-Montolio M, Singh LB, Findlay AD, Deodhar M, Foot JS, Jarolimek W, Timpson P, Erler JT, Cox TR. Chang J, et al. Among authors: foot js. Oncotarget. 2017 Apr 18;8(16):26066-26078. doi: 10.18632/oncotarget.15257. Oncotarget. 2017. PMID: 28199967 Free PMC article.
18 results