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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, Jaenisch R. Lyssiotis CA, et al. Among authors: foreman rk. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8912-7. doi: 10.1073/pnas.0903860106. Epub 2009 May 15. Proc Natl Acad Sci U S A. 2009. PMID: 19447925 Free PMC article.
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, Jaenisch R, Schultz PG. Staerk J, et al. Among authors: foreman rk. Angew Chem Int Ed Engl. 2011 Jun 14;50(25):5734-6. doi: 10.1002/anie.201101042. Epub 2011 May 5. Angew Chem Int Ed Engl. 2011. PMID: 21547985 Free PMC article. No abstract available.
Metastable pluripotent states in NOD-mouse-derived ESCs.
Hanna J, Markoulaki S, Mitalipova M, Cheng AW, Cassady JP, Staerk J, Carey BW, Lengner CJ, Foreman R, Love J, Gao Q, Kim J, Jaenisch R. Hanna J, et al. Among authors: foreman r. Cell Stem Cell. 2009 Jun 5;4(6):513-24. doi: 10.1016/j.stem.2009.04.015. Epub 2009 May 7. Cell Stem Cell. 2009. PMID: 19427283 Free PMC article.
Wnt signaling promotes reprogramming of somatic cells to pluripotency.
Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R. Marson A, et al. Among authors: foreman r. Cell Stem Cell. 2008 Aug 7;3(2):132-5. doi: 10.1016/j.stem.2008.06.019. Cell Stem Cell. 2008. PMID: 18682236 Free PMC article. No abstract available.
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