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Aging and neutrophils: there is still much to do.
Fortin CF, McDonald PP, Lesur O, Fülöp T Jr. Fortin CF, et al. Rejuvenation Res. 2008 Oct;11(5):873-82. doi: 10.1089/rej.2008.0750. Rejuvenation Res. 2008. PMID: 18847379 Review.
Impairment of SHP-1 down-regulation in the lipid rafts of human neutrophils under GM-CSF stimulation contributes to their age-related, altered functions.
Fortin CF, Larbi A, Lesur O, Douziech N, Fulop T Jr. Fortin CF, et al. J Leukoc Biol. 2006 May;79(5):1061-72. doi: 10.1189/jlb.0805481. Epub 2006 Feb 24. J Leukoc Biol. 2006. PMID: 16501054
GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals.
Fortin CF, Larbi A, Dupuis G, Lesur O, Fülöp T Jr. Fortin CF, et al. Biogerontology. 2007 Apr;8(2):173-87. doi: 10.1007/s10522-006-9067-1. Epub 2006 Nov 4. Biogerontology. 2007. PMID: 17086367
Translational control of human neutrophil responses by MNK1.
Fortin CF, Mayer TZ, Cloutier A, McDonald PP. Fortin CF, et al. J Leukoc Biol. 2013 Oct;94(4):693-703. doi: 10.1189/jlb.0113012. Epub 2013 Feb 11. J Leukoc Biol. 2013. PMID: 23401599
Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses.
Sylvain-Prévost S, Ear T, Simard FA, Fortin CF, Dubois CM, Flamand N, McDonald PP. Sylvain-Prévost S, et al. Among authors: fortin cf. J Immunol. 2015 Dec 1;195(11):5393-403. doi: 10.4049/jimmunol.1402752. Epub 2015 Oct 21. J Immunol. 2015. PMID: 26491199 Free article.
A class IA PI3K controls inflammatory cytokine production in human neutrophils.
Fortin CF, Cloutier A, Ear T, Sylvain-Prévost S, Mayer TZ, Bouchelaghem R, McDonald PP. Fortin CF, et al. Eur J Immunol. 2011 Jun;41(6):1709-19. doi: 10.1002/eji.201040945. Epub 2011 May 9. Eur J Immunol. 2011. PMID: 21469098 Free article.
Constitutive association of TGF-beta-activated kinase 1 with the IkappaB kinase complex in the nucleus and cytoplasm of human neutrophils and its impact on downstream processes.
Ear T, Fortin CF, Simard FA, McDonald PP. Ear T, et al. Among authors: fortin cf. J Immunol. 2010 Apr 1;184(7):3897-906. doi: 10.4049/jimmunol.0902958. Epub 2010 Mar 3. J Immunol. 2010. PMID: 20200282 Free article.
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