Fosang AJ - Search Results

1

ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan.

East CJ, Stanton H, Golub SB, Rogerson FM, Fosang AJ. East CJ, et al. Among authors: fosang aj. J Biol Chem. 2007 Mar 23;282(12):8632-40. doi: 10.1074/jbc.M605750200. Epub 2007 Jan 25. J Biol Chem. 2007. PMID: 17255106 Free article.

2

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro.

Stanton H, Rogerson FM, East CJ, Golub SB, Lawlor KE, Meeker CT, Little CB, Last K, Farmer PJ, Campbell IK, Fourie AM, Fosang AJ. Stanton H, et al. Among authors: fosang aj. Nature. 2005 Mar 31;434(7033):648-52. doi: 10.1038/nature03417. Nature. 2005. PMID: 15800625 Free article.

3

ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo.

Little CB, Mittaz L, Belluoccio D, Rogerson FM, Campbell IK, Meeker CT, Bateman JF, Pritchard MA, Fosang AJ. Little CB, et al. Among authors: fosang aj. Arthritis Rheum. 2005 May;52(5):1461-72. doi: 10.1002/art.21022. Arthritis Rheum. 2005. PMID: 15880348 Free article.

4

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair.

Little CB, Meeker CT, Golub SB, Lawlor KE, Farmer PJ, Smith SM, Fosang AJ. Little CB, et al. Among authors: fosang aj. J Clin Invest. 2007 Jun;117(6):1627-36. doi: 10.1172/JCI30765. Epub 2007 May 17. J Clin Invest. 2007. PMID: 17510707 Free PMC article.

5

Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice.

Ilic MZ, East CJ, Rogerson FM, Fosang AJ, Handley CJ. Ilic MZ, et al. Among authors: fosang aj. J Biol Chem. 2007 Dec 28;282(52):37420-8. doi: 10.1074/jbc.M703184200. Epub 2007 Oct 15. J Biol Chem. 2007. PMID: 17938173 Free article.

6

Evidence of a novel aggrecan-degrading activity in cartilage: Studies of mice deficient in both ADAMTS-4 and ADAMTS-5.

Rogerson FM, Stanton H, East CJ, Golub SB, Tutolo L, Farmer PJ, Fosang AJ. Rogerson FM, et al. Among authors: fosang aj. Arthritis Rheum. 2008 Jun;58(6):1664-73. doi: 10.1002/art.23458. Arthritis Rheum. 2008. PMID: 18512787 Free article.

7

Neoepitope antibodies against MMP-cleaved and aggrecanase-cleaved aggrecan.

Fosang AJ, Last K, Stanton H, Golub SB, Little CB, Brown L, Jackson DC. Fosang AJ, et al. Methods Mol Biol. 2010;622:312-47. doi: 10.1007/978-1-60327-299-5_19. Methods Mol Biol. 2010. PMID: 20135291

8

Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage.

Stanton H, Golub SB, Rogerson FM, Last K, Little CB, Fosang AJ. Stanton H, et al. Among authors: fosang aj. Nat Protoc. 2011 Mar;6(3):388-404. doi: 10.1038/nprot.2010.179. Epub 2011 Mar 3. Nat Protoc. 2011. PMID: 21372818

9

A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers.

Kosasih HJ, Last K, Rogerson FM, Golub SB, Gauci SJ, Russo VC, Stanton H, Wilson R, Lamande SR, Holden P, Fosang AJ. Kosasih HJ, et al. Among authors: fosang aj. J Biol Chem. 2016 Feb 12;291(7):3197-208. doi: 10.1074/jbc.M115.704817. Epub 2015 Dec 14. J Biol Chem. 2016. PMID: 26668318 Free PMC article.

10

ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5.

Rogerson FM, Last K, Golub SB, Gauci SJ, Stanton H, Bell KM, Fosang AJ. Rogerson FM, et al. Among authors: fosang aj. Int J Mol Sci. 2019 Jan 29;20(3):573. doi: 10.3390/ijms20030573. Int J Mol Sci. 2019. PMID: 30699963 Free PMC article.

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