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Monitoring Cyp2b10 mRNA expression at cessation of 2-year carcinogenesis bioassay in mouse liver provides evidence for a carcinogenic mechanism devoid of human relevance: the dalcetrapib experience.
Hoflack JC, Mueller L, Fowler S, Braendli-Baiocco A, Flint N, Kuhlmann O, Singer T, Roth A. Hoflack JC, et al. Among authors: fowler s. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):355-65. doi: 10.1016/j.taap.2012.01.014. Epub 2012 Jan 28. Toxicol Appl Pharmacol. 2012. PMID: 22293087
Minimizing DILI risk in drug discovery - A screening tool for drug candidates.
Schadt S, Simon S, Kustermann S, Boess F, McGinnis C, Brink A, Lieven R, Fowler S, Youdim K, Ullah M, Marschmann M, Zihlmann C, Siegrist YM, Cascais AC, Di Lenarda E, Durr E, Schaub N, Ang X, Starke V, Singer T, Alvarez-Sanchez R, Roth AB, Schuler F, Funk C. Schadt S, et al. Among authors: fowler s. Toxicol In Vitro. 2015 Dec 25;30(1 Pt B):429-37. doi: 10.1016/j.tiv.2015.09.019. Epub 2015 Sep 25. Toxicol In Vitro. 2015. PMID: 26407524
1,253 results