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Expression of vascular endothelial growth factor D is associated with hypoxia inducible factor (HIF-1alpha) and the HIF-1alpha target gene DEC1, but not lymph node metastasis in primary human breast carcinomas.
Currie MJ, Hanrahan V, Gunningham SP, Morrin HR, Frampton C, Han C, Robinson BA, Fox SB. Currie MJ, et al. Among authors: fox sb. J Clin Pathol. 2004 Aug;57(8):829-34. doi: 10.1136/jcp.2003.015644. J Clin Pathol. 2004. PMID: 15280403 Free PMC article.
COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment.
Generali D, Buffa FM, Deb S, Cummings M, Reid LE, Taylor M, Andreis D, Allevi G, Ferrero G, Byrne D, Martinotti M, Bottini A, Harris AL, Lakhani SR, Fox SB. Generali D, et al. Among authors: fox sb. Br J Cancer. 2014 Jul 8;111(1):46-54. doi: 10.1038/bjc.2014.236. Epub 2014 May 29. Br J Cancer. 2014. PMID: 24874483 Free PMC article. Clinical Trial.
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