Frödin M - Search Results

1

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

Frödin M, Gammeltoft S. Frödin M, et al. Mol Cell Endocrinol. 1999 May 25;151(1-2):65-77. doi: 10.1016/s0303-7207(99)00061-1. Mol Cell Endocrinol. 1999. PMID: 10411321 Review.

2

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation.

Hauge C, Antal TL, Hirschberg D, Doehn U, Thorup K, Idrissova L, Hansen K, Jensen ON, Jørgensen TJ, Biondi RM, Frödin M. Hauge C, et al. Among authors: frodin m. EMBO J. 2007 May 2;26(9):2251-61. doi: 10.1038/sj.emboj.7601682. Epub 2007 Apr 19. EMBO J. 2007. PMID: 17446865 Free PMC article.

3

RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.

Doehn U, Hauge C, Frank SR, Jensen CJ, Duda K, Nielsen JV, Cohen MS, Johansen JV, Winther BR, Lund LR, Winther O, Taunton J, Hansen SH, Frödin M. Doehn U, et al. Among authors: frodin m. Mol Cell. 2009 Aug 28;35(4):511-22. doi: 10.1016/j.molcel.2009.08.002. Mol Cell. 2009. PMID: 19716794 Free PMC article.

4

A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

Frödin M, Jensen CJ, Merienne K, Gammeltoft S. Frödin M, et al. EMBO J. 2000 Jun 15;19(12):2924-34. doi: 10.1093/emboj/19.12.2924. EMBO J. 2000. PMID: 10856237 Free PMC article.

5

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

Jensen CJ, Buch MB, Krag TO, Hemmings BA, Gammeltoft S, Frödin M. Jensen CJ, et al. Among authors: frodin m. J Biol Chem. 1999 Sep 17;274(38):27168-76. doi: 10.1074/jbc.274.38.27168. J Biol Chem. 1999. PMID: 10480933

6

Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells.

Silverman E, Frödin M, Gammeltoft S, Maller JL. Silverman E, et al. Among authors: frodin m. Mol Cell Biol. 2004 Dec;24(24):10573-83. doi: 10.1128/MCB.24.24.10573-10583.2004. Mol Cell Biol. 2004. PMID: 15572664 Free PMC article.

7

ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.

Zhao J, Yuan X, Frödin M, Grummt I. Zhao J, et al. Among authors: frodin m. Mol Cell. 2003 Feb;11(2):405-13. doi: 10.1016/s1097-2765(03)00036-4. Mol Cell. 2003. PMID: 12620228

8

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.

Frödin M, Antal TL, Dümmler BA, Jensen CJ, Deak M, Gammeltoft S, Biondi RM. Frödin M, et al. EMBO J. 2002 Oct 15;21(20):5396-407. doi: 10.1093/emboj/cdf551. EMBO J. 2002. PMID: 12374740 Free PMC article.

9

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.

Sapkota GP, Cummings L, Newell FS, Armstrong C, Bain J, Frodin M, Grauert M, Hoffmann M, Schnapp G, Steegmaier M, Cohen P, Alessi DR. Sapkota GP, et al. Among authors: frodin m. Biochem J. 2007 Jan 1;401(1):29-38. doi: 10.1042/BJ20061088. Biochem J. 2007. PMID: 17040210 Free PMC article.

10

Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types.

Dümmler BA, Hauge C, Silber J, Yntema HG, Kruse LS, Kofoed B, Hemmings BA, Alessi DR, Frödin M. Dümmler BA, et al. Among authors: frodin m. J Biol Chem. 2005 Apr 8;280(14):13304-14. doi: 10.1074/jbc.M408194200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632195

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