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Tyrosine nitration affects thymidylate synthase properties.
Dąbrowska-Maś E, Frączyk T, Ruman T, Radziszewska K, Wilk P, Cieśla J, Zieliński Z, Jurkiewicz A, Gołos B, Wińska P, Wałajtys-Rode E, Leś A, Nizioł J, Jarmuła A, Stefanowicz P, Szewczuk Z, Rode W. Dąbrowska-Maś E, et al. Among authors: fraczyk t. Org Biomol Chem. 2012 Jan 14;10(2):323-31. doi: 10.1039/c1ob06360j. Epub 2011 Nov 9. Org Biomol Chem. 2012. PMID: 22072032
Properties of phosphorylated thymidylate synthase.
Frączyk T, Ruman T, Wilk P, Palmowski P, Rogowska-Wrzesinska A, Cieśla J, Zieliński Z, Nizioł J, Jarmuła A, Maj P, Gołos B, Wińska P, Ostafil S, Wałajtys-Rode E, Shugar D, Rode W. Frączyk T, et al. Biochim Biophys Acta. 2015 Dec;1854(12):1922-1934. doi: 10.1016/j.bbapap.2015.08.007. Epub 2015 Aug 24. Biochim Biophys Acta. 2015. PMID: 26315778
Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
Jarmuła A, Wilk P, Maj P, Ludwiczak J, Dowierciał A, Banaszak K, Rypniewski W, Cieśla J, Dąbrowska M, Frączyk T, Bronowska AK, Jakowiecki J, Filipek S, Rode W. Jarmuła A, et al. Among authors: fraczyk t. J Mol Graph Model. 2017 Oct;77:33-50. doi: 10.1016/j.jmgm.2017.08.008. Epub 2017 Aug 12. J Mol Graph Model. 2017. PMID: 28826032
42 results