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The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.
Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005.
Immunity. 2018.
PMID: 30332629
Free PMC article.
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel B, Czimmerer Z, Halasz L, Boto P, Kolostyak Z, Poliska S, Berger WK, Tzerpos P, Nagy G, Horvath A, Hajas G, Cseh T, Nagy A, Sauer S, Francois-Deleuze J, Szatmari I, Bacsi A, Nagy L.
Daniel B, et al. Among authors: francois deleuze j.
Genes Dev. 2020 Nov 1;34(21-22):1474-1492. doi: 10.1101/gad.343038.120. Epub 2020 Oct 15.
Genes Dev. 2020.
PMID: 33060136
Free PMC article.
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Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.
Ferreira PG, Oti M, Barann M, Wieland T, Ezquina S, Friedländer MR, Rivas MA, Esteve-Codina A; GEUVADIS Consortium; Rosenstiel P, Strom TM, Lappalainen T, Guigó R, Sammeth M.
Ferreira PG, et al.
Sci Rep. 2016 Sep 12;6:32406. doi: 10.1038/srep32406.
Sci Rep. 2016.
PMID: 27617755
Free PMC article.
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The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Daniel B, Nagy G, Horvath A, Czimmerer Z, Cuaranta-Monroy I, Poliska S, Hays TT, Sauer S, Francois-Deleuze J, Nagy L.
Daniel B, et al. Among authors: francois deleuze j.
Nucleic Acids Res. 2018 May 18;46(9):4425-4439. doi: 10.1093/nar/gky157.
Nucleic Acids Res. 2018.
PMID: 29506156
Free PMC article.
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