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GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development.
Jones AR, Francis R, Schedl T. Jones AR, et al. Among authors: francis r. Dev Biol. 1996 Nov 25;180(1):165-83. doi: 10.1006/dbio.1996.0293. Dev Biol. 1996. PMID: 8948583
Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development.
Lee MH, Ohmachi M, Arur S, Nayak S, Francis R, Church D, Lambie E, Schedl T. Lee MH, et al. Among authors: francis r. Genetics. 2007 Dec;177(4):2039-62. doi: 10.1534/genetics.107.081356. Genetics. 2007. PMID: 18073423 Free PMC article.
emo-1, a Caenorhabditis elegans Sec61p gamma homologue, is required for oocyte development and ovulation.
Iwasaki K, McCarter J, Francis R, Schedl T. Iwasaki K, et al. Among authors: francis r. J Cell Biol. 1996 Aug;134(3):699-714. doi: 10.1083/jcb.134.3.699. J Cell Biol. 1996. PMID: 8707849 Free PMC article.
Alan R. Liss, Inc., New York. 77-95.), does not stain oz1 oocytes, a finding consistent with defective protein transport in the mutant. ...
Alan R. Liss, Inc., New York. 77-95.), does not stain oz1 oocytes, a finding consistent with defective protein transport in the mutan …
Analysis of the multiple roles of gld-1 in germline development: interactions with the sex determination cascade and the glp-1 signaling pathway.
Francis R, Maine E, Schedl T. Francis R, et al. Genetics. 1995 Feb;139(2):607-30. Genetics. 1995. PMID: 7713420 Free PMC article.
Muscle cell attachment in Caenorhabditis elegans.
Francis R, Waterston RH. Francis R, et al. J Cell Biol. 1991 Aug;114(3):465-79. doi: 10.1083/jcb.114.3.465. J Cell Biol. 1991. PMID: 1860880 Free PMC article.
gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans.
Francis R, Barton MK, Kimble J, Schedl T. Francis R, et al. Genetics. 1995 Feb;139(2):579-606. Genetics. 1995. PMID: 7713419 Free PMC article.
aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation.
Francis R, McGrath G, Zhang J, Ruddy DA, Sym M, Apfeld J, Nicoll M, Maxwell M, Hai B, Ellis MC, Parks AL, Xu W, Li J, Gurney M, Myers RL, Himes CS, Hiebsch R, Ruble C, Nye JS, Curtis D. Francis R, et al. Dev Cell. 2002 Jul;3(1):85-97. doi: 10.1016/s1534-5807(02)00189-2. Dev Cell. 2002. PMID: 12110170
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. Gumienny TL, et al. Among authors: francis r. Cell. 2001 Oct 5;107(1):27-41. doi: 10.1016/s0092-8674(01)00520-7. Cell. 2001. PMID: 11595183
The GluN2B subunit represents a major functional determinant of NMDA receptors in human induced pluripotent stem cell-derived cortical neurons.
Neagoe I, Liu C, Stumpf A, Lu Y, He D, Francis R, Chen J, Reynen P, Alaoui-Ismaili MH, Fukui H. Neagoe I, et al. Among authors: francis r. Stem Cell Res. 2018 Apr;28:105-114. doi: 10.1016/j.scr.2018.02.002. Epub 2018 Feb 8. Stem Cell Res. 2018. PMID: 29454156
The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.
Senger K, Pham VC, Varfolomeev E, Hackney JA, Corzo CA, Collier J, Lau VWC, Huang Z, Hamidzhadeh K, Caplazi P, Peng I, Setiadi AF, Francis R, Paler-Martinez A, Kwon YC, Ramirez-Carrozzi V, Sun Y, Grigg PW, Roose-Girma M, Jeet S, Barck KH, Pham A, Ota N, Ha C, Stinson J, Guillory J, Tam L, Modrusan Z, Emson C, McKenzie BS, Townsend MJ, Carano RAD, Warming S, Vucic D, DeVoss J, Lee WP, Lill JR, Zarrin AA. Senger K, et al. Among authors: francis r. Sci Signal. 2017 Apr 18;10(475):eaah4273. doi: 10.1126/scisignal.aah4273. Sci Signal. 2017. PMID: 28420753
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