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Complying with the European Clinical Trials directive while surviving the administrative pressure - an alternative approach to toxicity registration in a cancer trial.
Frandsen TL, Heyman M, Abrahamsson J, Vettenranta K, Åsberg A, Vaitkeviciene G, Pruunsild K, Toft N, Birgens H, Hallböök H, Quist-Paulsen P, Griškevičius L, Helt L, Hansen BV, Schmiegelow K. Frandsen TL, et al. Eur J Cancer. 2014 Jan;50(2):251-9. doi: 10.1016/j.ejca.2013.09.027. Epub 2013 Nov 11. Eur J Cancer. 2014. PMID: 24231337
Individualized toxicity-titrated 6-mercaptopurine increments during high-dose methotrexate consolidation treatment of lower risk childhood acute lymphoblastic leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot study.
Frandsen TL, Abrahamsson J, Lausen B, Vettenranta K, Heyman M, Behrentz M, Castor A, Wehner PS, Frost BM, Andersen EW, Schmiegelow K. Frandsen TL, et al. Br J Haematol. 2011 Oct;155(2):244-7. doi: 10.1111/j.1365-2141.2011.08835.x. Epub 2011 Aug 18. Br J Haematol. 2011. PMID: 21848519 Free article. Clinical Trial.
Asparaginase-associated pancreatitis in children.
Raja RA, Schmiegelow K, Frandsen TL. Raja RA, et al. Among authors: frandsen tl. Br J Haematol. 2012 Oct;159(1):18-27. doi: 10.1111/bjh.12016. Epub 2012 Aug 22. Br J Haematol. 2012. PMID: 22909259 Free article. Review.
Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes.
Ebbesen MS, Nersting J, Jacobsen JH, Frandsen TL, Vettenranta K, Abramsson J, Wesenberg F, Schmiegelow K. Ebbesen MS, et al. Among authors: frandsen tl. J Clin Pharmacol. 2013 Jun;53(6):670-4. doi: 10.1002/jcph.81. Epub 2013 Apr 15. J Clin Pharmacol. 2013. PMID: 23585236 Clinical Trial. No abstract available.
Asparaginase-associated pancreatitis in children with acute lymphoblastic leukaemia in the NOPHO ALL2008 protocol.
Raja RA, Schmiegelow K, Albertsen BK, Prunsild K, Zeller B, Vaitkeviciene G, Abrahamsson J, Heyman M, Taskinen M, Harila-Saari A, Kanerva J, Frandsen TL; Nordic Society of Paediatric Haematology and Oncology (NOPHO) group. Raja RA, et al. Among authors: frandsen tl. Br J Haematol. 2014 Apr;165(1):126-33. doi: 10.1111/bjh.12733. Epub 2014 Jan 15. Br J Haematol. 2014. PMID: 24428625 Free article.
Clinical features and early treatment response of central nervous system involvement in childhood acute lymphoblastic leukemia.
Levinsen M, Taskinen M, Abrahamsson J, Forestier E, Frandsen TL, Harila-Saari A, Heyman M, Jonsson OG, Lähteenmäki PM, Lausen B, Vaitkevičienė G, Asberg A, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology (NOPHO). Levinsen M, et al. Among authors: frandsen tl. Pediatr Blood Cancer. 2014 Aug;61(8):1416-21. doi: 10.1002/pbc.24981. Epub 2014 Feb 12. Pediatr Blood Cancer. 2014. PMID: 24623619 Clinical Trial.
Cerebral sinus venous thromboses in children with acute lymphoblastic leukaemia - a multicentre study from the Nordic Society of Paediatric Haematology and Oncology.
Ranta S, Tuckuviene R, Mäkipernaa A, Albertsen BK, Frisk T, Tedgård U, Jónsson ÓG, Pruunsild K, Gretenkort Andersson N, Winther Gunnes M, Saulyte Trakymiene S, Frandsen T, Heyman M, Ruud E, Helgestad J. Ranta S, et al. Br J Haematol. 2015 Feb;168(4):547-52. doi: 10.1111/bjh.13162. Epub 2014 Oct 7. Br J Haematol. 2015. PMID: 25288392 Free article.
Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.
Levinsen M, Rosthøj S, Nygaard U, Heldrup J, Harila-Saari A, Jonsson OG, Bechensteen AG, Abrahamsson J, Lausen B, Frandsen TL, Weinshilboum RM, Schmiegelow K. Levinsen M, et al. Among authors: frandsen tl. Cancer Chemother Pharmacol. 2015 Jan;75(1):59-66. doi: 10.1007/s00280-014-2613-7. Epub 2014 Oct 28. Cancer Chemother Pharmacol. 2015. PMID: 25347948 Free PMC article.
84 results