Small Fiber Neuropathy After SARS-CoV-2 Infection and Vaccination: A Case-Based Comparison

Beth Schwartz; Shyam Moudgil; Frank Pollina; Ashish Bhargava

doi:10.7759/cureus.43600

Small Fiber Neuropathy After SARS-CoV-2 Infection and Vaccination: A Case-Based Comparison

Cureus. 2023 Aug 16;15(8):e43600. doi: 10.7759/cureus.43600. eCollection 2023 Aug.

Authors

Beth Schwartz¹, Shyam Moudgil², Frank Pollina³, Ashish Bhargava¹

Affiliations

¹ Internal Medicine, Ascension St. John Hospital, Detroit, USA.
² Neurology, Ascension St. John Hospital, Detroit, USA.
³ Physical Medicine and Rehabilitation, Ascension St. John Hospital, Detroit, USA.

Abstract

COVID-19-associated neuropathies, whether post-infection or post-vaccination, have not been fully described. A variety of theories exist to explain these phenomena, many of them centering on immune dysregulation. We aim to contribute to the discussion on the similarities and differences behind the two conditions and to bolster the call for further research to be done in this area. We will discuss two different case presentations, one patient experiencing a post-COVID-19 infection neuropathy and the other experiencing a post-COVID-19 vaccination neuropathy.

Keywords: covid-19; covid-19 and neurology; covid-19 mrna vaccine; long covid symptoms; sars-cov-2; small fiber neuropathy.

Publication types

Case Reports