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Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance.
Retrovirology. 2009 Feb 11;6:14. doi: 10.1186/1742-4690-6-14.
Retrovirology. 2009.
PMID: 19210791
Free PMC article.
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture.
Brenner BG, Oliveira M, Doualla-Bell F, Moisi DD, Ntemgwa M, Frankel F, Essex M, Wainberg MA.
Brenner BG, et al.
AIDS. 2006 Jun 12;20(9):F9-13. doi: 10.1097/01.aids.0000232228.88511.0b.
AIDS. 2006.
PMID: 16816549
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Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase.
Frankel FA, Marchand B, Turner D, Götte M, Wainberg MA.
Frankel FA, et al.
Antimicrob Agents Chemother. 2005 Jul;49(7):2657-64. doi: 10.1128/AAC.49.7.2657-2664.2005.
Antimicrob Agents Chemother. 2005.
PMID: 15980333
Free PMC article.
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Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations.
Frankel FA, Invernizzi CF, Oliveira M, Wainberg MA.
Frankel FA, et al.
AIDS. 2007 Mar 30;21(6):665-75. doi: 10.1097/QAD.0b013e3280187505.
AIDS. 2007.
PMID: 17413687
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Kinetics of inhibition of HIV type 1 reverse transcriptase-bearing NRTI-associated mutations by apricitabine triphosphate.
Frankel FA, Coutsinos D, Xu H, Wainberg MA.
Frankel FA, et al.
Antivir Chem Chemother. 2007;18(2):93-101. doi: 10.1177/095632020701800205.
Antivir Chem Chemother. 2007.
PMID: 17542154
Free article.
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Arginine methylation of the HIV-1 nucleocapsid protein results in its diminished function.
Invernizzi CF, Xie B, Frankel FA, Feldhammer M, Roy BB, Richard S, Wainberg MA.
Invernizzi CF, et al. Among authors: frankel fa.
AIDS. 2007 Apr 23;21(7):795-805. doi: 10.1097/QAD.0b013e32803277ae.
AIDS. 2007.
PMID: 17415034
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