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Differential effects of THC- or CBD-rich cannabis extracts on working memory in rats.
Fadda P, Robinson L, Fratta W, Pertwee RG, Riedel G. Fadda P, et al. Among authors: fratta w. Neuropharmacology. 2004 Dec;47(8):1170-9. doi: 10.1016/j.neuropharm.2004.08.009. Neuropharmacology. 2004. PMID: 15567426
Adolescent Δ(9)-Tetrahydrocannabinol Exposure Alters WIN55,212-2 Self-Administration in Adult Rats.
Scherma M, Dessì C, Muntoni AL, Lecca S, Satta V, Luchicchi A, Pistis M, Panlilio LV, Fattore L, Goldberg SR, Fratta W, Fadda P. Scherma M, et al. Among authors: fratta w. Neuropsychopharmacology. 2016 Apr;41(5):1416-26. doi: 10.1038/npp.2015.295. Epub 2015 Sep 21. Neuropsychopharmacology. 2016. PMID: 26388146 Free PMC article.
The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition.
Scherma M, Medalie J, Fratta W, Vadivel SK, Makriyannis A, Piomelli D, Mikics E, Haller J, Yasar S, Tanda G, Goldberg SR. Scherma M, et al. Among authors: fratta w. Neuropharmacology. 2008 Jan;54(1):129-40. doi: 10.1016/j.neuropharm.2007.08.011. Epub 2007 Aug 19. Neuropharmacology. 2008. PMID: 17904589 Free PMC article.
Cannabinoid CB(1) antagonist SR 141716A attenuates reinstatement of heroin self-administration in heroin-abstinent rats.
Fattore L, Spano S, Cossu G, Deiana S, Fadda P, Fratta W. Fattore L, et al. Among authors: fratta w. Neuropharmacology. 2005 Jun;48(8):1097-104. doi: 10.1016/j.neuropharm.2005.01.022. Epub 2005 Mar 29. Neuropharmacology. 2005. PMID: 15910886
Scopolamine and MK801-induced working memory deficits in rats are not reversed by CBD-rich cannabis extracts.
Fadda P, Robinson L, Fratta W, Pertwee RG, Riedel G. Fadda P, et al. Among authors: fratta w. Behav Brain Res. 2006 Apr 3;168(2):307-11. doi: 10.1016/j.bbr.2005.11.022. Epub 2006 Jan 6. Behav Brain Res. 2006. PMID: 16406104
Towards this end, we have recently shown that high concentrations of plant extracts rich in cannabidiol (CBD) can reverse working memory deficits induced by Delta9-THC which is a remaining contaminant of this extract [Fadda P, Robinson L, Fratta W, Pertwee RG, Riede …
Towards this end, we have recently shown that high concentrations of plant extracts rich in cannabidiol (CBD) can reverse working memory def …
The GABAB receptor agonist baclofen prevents heroin-induced reinstatement of heroin-seeking behavior in rats.
Spano MS, Fattore L, Fratta W, Fadda P. Spano MS, et al. Among authors: fratta w. Neuropharmacology. 2007 Jun;52(7):1555-62. doi: 10.1016/j.neuropharm.2007.02.012. Epub 2007 Mar 14. Neuropharmacology. 2007. PMID: 17451755
Pharmacological modulation of the endocannabinoid signalling alters binge-type eating behaviour in female rats.
Scherma M, Fattore L, Satta V, Businco F, Pigliacampo B, Goldberg SR, Dessi C, Fratta W, Fadda P. Scherma M, et al. Among authors: fratta w. Br J Pharmacol. 2013 Jun;169(4):820-33. doi: 10.1111/bph.12014. Br J Pharmacol. 2013. PMID: 23072421 Free PMC article.
Chronic blockade of CB(1) receptors reverses startle gating deficits and associated neurochemical alterations in rats reared in isolation.
Zamberletti E, Piscitelli F, Cadeddu F, Rubino T, Fratta W, Fadda P, Di Marzo V, Parolaro D. Zamberletti E, et al. Among authors: fratta w. Br J Pharmacol. 2012 Dec;167(8):1652-64. doi: 10.1111/j.1476-5381.2012.02095.x. Br J Pharmacol. 2012. PMID: 22762735 Free PMC article.
Male and female rats differ in brain cannabinoid CB1 receptor density and function and in behavioural traits predisposing to drug addiction: effect of ovarian hormones.
Castelli MP, Fadda P, Casu A, Spano MS, Casti A, Fratta W, Fattore L. Castelli MP, et al. Among authors: fratta w. Curr Pharm Des. 2014;20(13):2100-13. doi: 10.2174/13816128113199990430. Epub 2013 Jul 9. Curr Pharm Des. 2014. PMID: 23829370
The anabolic steroid nandrolone alters cannabinoid self-administration and brain CB1 receptor density and function.
Struik D, Fadda P, Zara T, Zamberletti E, Rubino T, Parolaro D, Fratta W, Fattore L. Struik D, et al. Among authors: fratta w. Pharmacol Res. 2017 Jan;115:209-217. doi: 10.1016/j.phrs.2016.11.031. Epub 2016 Nov 24. Pharmacol Res. 2017. PMID: 27890818
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