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Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients.
Farup J, Just J, de Paoli F, Lin L, Jensen JB, Billeskov T, Roman IS, Cömert C, Møller AB, Madaro L, Groppa E, Fred RG, Kampmann U, Gormsen LC, Pedersen SB, Bross P, Stevnsner T, Eldrup N, Pers TH, Rossi FMV, Puri PL, Jessen N. Farup J, et al. Among authors: fred rg. Cell Metab. 2021 Nov 2;33(11):2201-2214.e11. doi: 10.1016/j.cmet.2021.10.001. Epub 2021 Oct 21. Cell Metab. 2021. PMID: 34678202 Free PMC article.
Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies.
Jensen JB, Møller AB, Just J, Mose M, de Paoli FV, Billeskov TB, Fred RG, Pers TH, Pedersen SB, Petersen KK, Bjerre M, Farup J, Jessen N. Jensen JB, et al. Among authors: fred rg. Am J Physiol Cell Physiol. 2021 Aug 1;321(2):C257-C268. doi: 10.1152/ajpcell.00127.2021. Epub 2021 Jun 9. Am J Physiol Cell Physiol. 2021. PMID: 34106790 Free article.
CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N. Abels M, et al. Among authors: fred rg. Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23. Diabetologia. 2016. PMID: 27338624
Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels.
Lindqvist A, Shcherbina L, Prasad RB, Miskelly MG, Abels M, Martínez-Lopéz JA, Fred RG, Nergård BJ, Hedenbro J, Groop L, Hjerling-Leffler J, Wierup N. Lindqvist A, et al. Among authors: fred rg. Mol Cell Endocrinol. 2020 Jul 1;511:110835. doi: 10.1016/j.mce.2020.110835. Epub 2020 May 3. Mol Cell Endocrinol. 2020. PMID: 32371087 Free article.
18 results