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Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy.
Zhang W, Molehin AJ, Rojo JU, Sudduth J, Ganapathy PK, Kim E, Siddiqui AJ, Freeborn J, Sennoune SR, May J, Lazarus S, Nguyen C, Redman WK, Ahmad G, Torben W, Karmakar S, Le L, Kottapalli KR, Kottapalli P, Wolf RF, Papin JF, Carey D, Gray SA, Bergthold JD, Damian RT, Mayer BT, Marks F, Reed SG, Carter D, Siddiqui AA. Zhang W, et al. Among authors: freeborn j. Ann N Y Acad Sci. 2018 Aug;1425(1):38-51. doi: 10.1111/nyas.13942. Ann N Y Acad Sci. 2018. PMID: 30133707 Free PMC article.
Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter.
Siddiqui AJ, Molehin AJ, Zhang W, Ganapathy PK, Kim E, Rojo JU, Redman WK, Sennoune SR, Sudduth J, Freeborn J, Hunter D, Kottapalli KR, Kottapalli P, Wettashinghe R, van Dam GJ, Corstjens PLAM, Papin JF, Carey D, Torben W, Ahmad G, Siddiqui AA. Siddiqui AJ, et al. Among authors: freeborn j. Ann N Y Acad Sci. 2018 Aug;1425(1):19-37. doi: 10.1111/nyas.13866. Epub 2018 Jun 11. Ann N Y Acad Sci. 2018. PMID: 29888790
Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identification of Putative Correlative Markers of Protection.
Zhang W, Le L, Ahmad G, Molehin AJ, Siddiqui AJ, Torben W, Karmakar S, Rojo JU, Sennoune S, Lazarus S, Khatoon S, Freeborn J, Sudduth J, Rezk AF, Carey D, Wolf RF, Papin JF, Damian R, Gray SA, Marks F, Carter D, Siddiqui AA. Zhang W, et al. Among authors: freeborn j. Front Immunol. 2020 Jun 19;11:1246. doi: 10.3389/fimmu.2020.01246. eCollection 2020. Front Immunol. 2020. PMID: 32636844 Free PMC article.
Lactobacillus reuteri DSM 17938 feeding of healthy newborn mice regulates immune responses while modulating gut microbiota and boosting beneficial metabolites.
Liu Y, Tian X, He B, Hoang TK, Taylor CM, Blanchard E, Freeborn J, Park S, Luo M, Couturier J, Tran DQ, Roos S, Wu G, Rhoads JM. Liu Y, et al. Among authors: freeborn j. Am J Physiol Gastrointest Liver Physiol. 2019 Dec 1;317(6):G824-G838. doi: 10.1152/ajpgi.00107.2019. Epub 2019 Sep 4. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 31482733 Free PMC article.
Limosilactobacillus reuteri and Lacticaseibacillus rhamnosus GG differentially affect gut microbes and metabolites in mice with Treg deficiency.
Liu Y, Hoang TK, Taylor CM, Park ES, Freeborn J, Luo M, Roos S, Rhoads JM. Liu Y, et al. Among authors: freeborn j. Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1;320(6):G969-G981. doi: 10.1152/ajpgi.00072.2021. Epub 2021 Mar 31. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33787352 Free PMC article.
Bacteroides ovatus Promotes IL-22 Production and Reduces Trinitrobenzene Sulfonic Acid-Driven Colonic Inflammation.
Ihekweazu FD, Engevik MA, Ruan W, Shi Z, Fultz R, Engevik KA, Chang-Graham AL, Freeborn J, Park ES, Venable S, Horvath TD, Haidacher SJ, Haag AM, Goodwin A, Schady DA, Hyser JM, Spinler JK, Liu Y, Versalovic J. Ihekweazu FD, et al. Among authors: freeborn j. Am J Pathol. 2021 Apr;191(4):704-719. doi: 10.1016/j.ajpath.2021.01.009. Epub 2021 Jan 28. Am J Pathol. 2021. PMID: 33516788 Free PMC article.
13 results