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Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.
Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Freedman BS, et al. Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715. Nat Commun. 2015. PMID: 26493500 Free PMC article.
Directed differentiation of pluripotent stem cells to kidney cells.
Lam AQ, Freedman BS, Bonventre JV. Lam AQ, et al. Among authors: freedman bs. Semin Nephrol. 2014 Jul;34(4):445-61. doi: 10.1016/j.semnephrol.2014.06.011. Epub 2014 Jun 13. Semin Nephrol. 2014. PMID: 25217273 Free PMC article. Review.
Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks.
Pang P, Abbott M, Chang SL, Abdi M, Chauhan N, Mistri M, Ghofrani J, Fucci QA, Walker C, Leonardi C, Grady S, Halim A, Hoffman R, Lu T, Cao H, Tullius SG, Malek S, Kumar S, Steele G, Kibel A, Freedman BS, Waikar SS, Siedlecki AM. Pang P, et al. Among authors: freedman bs. Kidney Int. 2017 Jan;91(1):129-143. doi: 10.1016/j.kint.2016.07.037. Epub 2016 Sep 29. Kidney Int. 2017. PMID: 27692806 Free PMC article.
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development.
Kim YK, Refaeli I, Brooks CR, Jing P, Gulieva RE, Hughes MR, Cruz NM, Liu Y, Churchill AJ, Wang Y, Fu H, Pippin JW, Lin LY, Shankland SJ, Vogl AW, McNagny KM, Freedman BS. Kim YK, et al. Among authors: freedman bs. Stem Cells. 2017 Dec;35(12):2366-2378. doi: 10.1002/stem.2707. Epub 2017 Sep 29. Stem Cells. 2017. PMID: 28905451 Free PMC article.
56 results