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The B7-CD28 superfamily.
Sharpe AH, Freeman GJ. Sharpe AH, et al. Among authors: freeman gj. Nat Rev Immunol. 2002 Feb;2(2):116-26. doi: 10.1038/nri727. Nat Rev Immunol. 2002. PMID: 11910893 Review.
Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression.
Nabavi N, Freeman GJ, Gault A, Godfrey D, Nadler LM, Glimcher LH. Nabavi N, et al. Among authors: freeman gj. Nature. 1992 Nov 19;360(6401):266-8. doi: 10.1038/360266a0. Nature. 1992. PMID: 1279442
CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.
Freeman GJ, Lombard DB, Gimmi CD, Brod SA, Lee K, Laning JC, Hafler DA, Dorf ME, Gray GS, Reiser H, et al. Freeman GJ, et al. J Immunol. 1992 Dec 15;149(12):3795-801. J Immunol. 1992. PMID: 1281186
Murine B7 antigen provides a sufficient costimulatory signal for antigen-specific and MHC-restricted T cell activation.
Galvin F, Freeman GJ, Razi-Wolf Z, Hall W Jr, Benacerraf B, Nadler L, Reiser H. Galvin F, et al. Among authors: freeman gj. J Immunol. 1992 Dec 15;149(12):3802-8. J Immunol. 1992. PMID: 1281187
Murine B7 antigen provides an efficient costimulatory signal for activation of murine T lymphocytes via the T-cell receptor/CD3 complex.
Reiser H, Freeman GJ, Razi-Wolf Z, Gimmi CD, Benacerraf B, Nadler LM. Reiser H, et al. Among authors: freeman gj. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):271-5. doi: 10.1073/pnas.89.1.271. Proc Natl Acad Sci U S A. 1992. PMID: 1370349 Free PMC article.
The gene for B7, a costimulatory signal for T-cell activation, maps to chromosomal region 3q13.3-3q21.
Freeman GJ, Disteche CM, Gribben JG, Adler DA, Freedman AS, Dougery J, Nadler LM. Freeman GJ, et al. Blood. 1992 Jan 15;79(2):489-94. Blood. 1992. PMID: 1370389
Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells.
Vandenberghe P, Freeman GJ, Nadler LM, Fletcher MC, Kamoun M, Turka LA, Ledbetter JA, Thompson CB, June CH. Vandenberghe P, et al. Among authors: freeman gj. J Exp Med. 1992 Apr 1;175(4):951-60. doi: 10.1084/jem.175.4.951. J Exp Med. 1992. PMID: 1372649 Free PMC article.
Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells.
Razi-Wolf Z, Freeman GJ, Galvin F, Benacerraf B, Nadler L, Reiser H. Razi-Wolf Z, et al. Among authors: freeman gj. Proc Natl Acad Sci U S A. 1992 May 1;89(9):4210-4. doi: 10.1073/pnas.89.9.4210. Proc Natl Acad Sci U S A. 1992. PMID: 1373896 Free PMC article.
Early signaling defects in human T cells anergized by T cell presentation of autoantigen.
LaSalle JM, Tolentino PJ, Freeman GJ, Nadler LM, Hafler DA. LaSalle JM, et al. Among authors: freeman gj. J Exp Med. 1992 Jul 1;176(1):177-86. doi: 10.1084/jem.176.1.177. J Exp Med. 1992. PMID: 1535366 Free PMC article.
B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.
Gimmi CD, Freeman GJ, Gribben JG, Sugita K, Freedman AS, Morimoto C, Nadler LM. Gimmi CD, et al. Among authors: freeman gj. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6575-9. doi: 10.1073/pnas.88.15.6575. Proc Natl Acad Sci U S A. 1991. PMID: 1650475 Free PMC article.
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