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17 results
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Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling.
Freeman KW, Bowman BR, Zetter BR. Freeman KW, et al. FASEB J. 2011 Mar;25(3):907-15. doi: 10.1096/fj.10-169417. Epub 2010 Nov 24. FASEB J. 2011. PMID: 21106936
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis.
Finlayson AE, Freeman KW. Finlayson AE, et al. Among authors: freeman kw. PLoS One. 2009 Nov 18;4(11):e7833. doi: 10.1371/journal.pone.0007833. PLoS One. 2009. PMID: 19924305 Free PMC article.
Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition.
Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM. Acevedo VD, et al. Among authors: freeman kw. Cancer Cell. 2007 Dec;12(6):559-71. doi: 10.1016/j.ccr.2007.11.004. Cancer Cell. 2007. PMID: 18068632 Free article.
Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland.
Welm BE, Freeman KW, Chen M, Contreras A, Spencer DM, Rosen JM. Welm BE, et al. Among authors: freeman kw. J Cell Biol. 2002 May 13;157(4):703-14. doi: 10.1083/jcb.200107119. Epub 2002 May 13. J Cell Biol. 2002. PMID: 12011115 Free PMC article.
Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2.
Winter SF, Acevedo VD, Gangula RD, Freeman KW, Spencer DM, Greenberg NM. Winter SF, et al. Among authors: freeman kw. Oncogene. 2007 Jul 26;26(34):4897-907. doi: 10.1038/sj.onc.1210288. Epub 2007 Feb 12. Oncogene. 2007. PMID: 17297442
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.
Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Freeman KW, et al. Cancer Res. 2003 Dec 1;63(23):8256-63. Cancer Res. 2003. PMID: 14678983
Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Freeman KW, et al. Cancer Res. 2003 Oct 1;63(19):6237-43. Cancer Res. 2003. PMID: 14559809
An inducible system for the study of FGF signalling in early amphibian development.
Pownall ME, Welm BE, Freeman KW, Spencer DM, Rosen JM, Isaacs HV. Pownall ME, et al. Among authors: freeman kw. Dev Biol. 2003 Apr 1;256(1):89-99. doi: 10.1016/s0012-1606(02)00120-3. Dev Biol. 2003. PMID: 12654294
Improved artificial death switches based on caspases and FADD.
Fan L, Freeman KW, Khan T, Pham E, Spencer DM. Fan L, et al. Among authors: freeman kw. Hum Gene Ther. 1999 Sep 20;10(14):2273-85. doi: 10.1089/10430349950016924. Hum Gene Ther. 1999. PMID: 10515447
Synthetic activation of caspases: artificial death switches.
MacCorkle RA, Freeman KW, Spencer DM. MacCorkle RA, et al. Among authors: freeman kw. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3655-60. doi: 10.1073/pnas.95.7.3655. Proc Natl Acad Sci U S A. 1998. PMID: 9520421 Free PMC article.
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