Freeman RS - Search Results

1

Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons.

Lomb DJ, Desouza LA, Franklin JL, Freeman RS. Lomb DJ, et al. Among authors: freeman rs. Mol Pharmacol. 2009 May;75(5):1198-209. doi: 10.1124/mol.108.053157. Epub 2009 Feb 9. Mol Pharmacol. 2009. PMID: 19204094 Free PMC article.

2

Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation.

Lomb DJ, Straub JA, Freeman RS. Lomb DJ, et al. Among authors: freeman rs. J Neurochem. 2007 Dec;103(5):1897-906. doi: 10.1111/j.1471-4159.2007.04873.x. Epub 2007 Aug 30. J Neurochem. 2007. PMID: 17760870 Free article.

3

Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity.

Barone MC, Desouza LA, Freeman RS. Barone MC, et al. Among authors: freeman rs. J Neurochem. 2008 Jul;106(2):734-45. doi: 10.1111/j.1471-4159.2008.05427.x. Epub 2008 Apr 14. J Neurochem. 2008. PMID: 18419764 Free PMC article.

4

NGF deprivation-induced gene expression: after ten years, where do we stand?

Freeman RS, Burch RL, Crowder RJ, Lomb DJ, Schoell MC, Straub JA, Xie L. Freeman RS, et al. Prog Brain Res. 2004;146:111-26. doi: 10.1016/S0079-6123(03)46008-1. Prog Brain Res. 2004. PMID: 14699960 Review.

5

Inhibition of NGF deprivation-induced death by low oxygen involves suppression of BIMEL and activation of HIF-1.

Xie L, Johnson RS, Freeman RS. Xie L, et al. Among authors: freeman rs. J Cell Biol. 2005 Mar 14;168(6):911-20. doi: 10.1083/jcb.200407079. J Cell Biol. 2005. PMID: 15767462 Free PMC article.

6

Analysis of the NF-kappa B and PI 3-kinase/Akt survival pathways in nerve growth factor-dependent neurons.

Sarmiere PD, Freeman RS. Sarmiere PD, et al. Among authors: freeman rs. Mol Cell Neurosci. 2001 Sep;18(3):320-31. doi: 10.1006/mcne.2001.1021. Mol Cell Neurosci. 2001. PMID: 11591132

7

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

Crowder RJ, Freeman RS. Crowder RJ, et al. Among authors: freeman rs. J Neurosci. 1998 Apr 15;18(8):2933-43. doi: 10.1523/JNEUROSCI.18-08-02933.1998. J Neurosci. 1998. PMID: 9526010 Free PMC article.

8

Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons.

Maggirwar SB, Sarmiere PD, Dewhurst S, Freeman RS. Maggirwar SB, et al. Among authors: freeman rs. J Neurosci. 1998 Dec 15;18(24):10356-65. doi: 10.1523/JNEUROSCI.18-24-10356.1998. J Neurosci. 1998. PMID: 9852573 Free PMC article.

9

Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons.

Lipscomb EA, Sarmiere PD, Crowder RJ, Freeman RS. Lipscomb EA, et al. Among authors: freeman rs. J Neurochem. 1999 Jul;73(1):429-32. doi: 10.1046/j.1471-4159.1999.0730429.x. J Neurochem. 1999. PMID: 10386996 Free article.

10

Targeting hypoxia-inducible factor (HIF) as a therapeutic strategy for CNS disorders.

Freeman RS, Barone MC. Freeman RS, et al. Curr Drug Targets CNS Neurol Disord. 2005 Feb;4(1):85-92. doi: 10.2174/1568007053005154. Curr Drug Targets CNS Neurol Disord. 2005. PMID: 15723616 Review.

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