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Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib.
Wind S, Schmid U, Freiwald M, Marzin K, Lotz R, Ebner T, Stopfer P, Dallinger C. Wind S, et al. Among authors: Freiwald M. Clin Pharmacokinet. 2019 Sep;58(9):1131-1147. doi: 10.1007/s40262-019-00766-0. Clin Pharmacokinet. 2019. PMID: 31016670 Free PMC article. Review.
Modeling Exposure-Driven Adverse Event Time Courses in Oncology Exemplified by Afatinib.
Niebecker R, Maas H, Staab A, Freiwald M, Karlsson MO. Niebecker R, et al. Among authors: Freiwald M. CPT Pharmacometrics Syst Pharmacol. 2019 Apr;8(4):230-239. doi: 10.1002/psp4.12384. Epub 2019 Feb 27. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30681293 Free PMC article.
Population pharmacokinetics of nintedanib, an inhibitor of tyrosine kinases, in patients with non-small cell lung cancer or idiopathic pulmonary fibrosis.
Schmid U, Liesenfeld KH, Fleury A, Dallinger C, Freiwald M. Schmid U, et al. Among authors: Freiwald M. Cancer Chemother Pharmacol. 2018 Jan;81(1):89-101. doi: 10.1007/s00280-017-3452-0. Epub 2017 Nov 8. Cancer Chemother Pharmacol. 2018. PMID: 29119292 Free PMC article.
Continued use of afatinib with the addition of cetuximab after progression on afatinib in patients with EGFR mutation-positive non-small-cell lung cancer and acquired resistance to gefitinib or erlotinib.
Horn L, Gettinger S, Camidge DR, Smit EF, Janjigian YY, Miller VA, Pao W, Freiwald M, Fan J, Wang B, Chand VK, Groen HJM. Horn L, et al. Among authors: Freiwald M. Lung Cancer. 2017 Nov;113:51-58. doi: 10.1016/j.lungcan.2017.08.014. Epub 2017 Aug 31. Lung Cancer. 2017. PMID: 29110849 Free article. Clinical Trial.
Clinical Pharmacokinetics and Pharmacodynamics of Afatinib.
Wind S, Schnell D, Ebner T, Freiwald M, Stopfer P. Wind S, et al. Among authors: Freiwald M. Clin Pharmacokinet. 2017 Mar;56(3):235-250. doi: 10.1007/s40262-016-0440-1. Clin Pharmacokinet. 2017. PMID: 27470518 Free PMC article. Review.
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