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Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation.
Houten SM, Frenkel J, Waterham HR. Houten SM, et al. Among authors: frenkel j. Cell Mol Life Sci. 2003 Jun;60(6):1118-34. doi: 10.1007/s00018-003-2296-4. Cell Mol Life Sci. 2003. PMID: 12861380 Review.
Validation of the auto-inflammatory diseases activity index (AIDAI) for hereditary recurrent fever syndromes.
Piram M, Koné-Paut I, Lachmann HJ, Frenkel J, Ozen S, Kuemmerle-Deschner J, Stojanov S, Simon A, Finetti M, Sormani MP, Martini A, Gattorno M, Ruperto N; EUROFEVER, EUROTRAPS and the Paediatric Rheumatology International Trials Organisation (PRINTO) networks. Piram M, et al. Among authors: frenkel j. Ann Rheum Dis. 2014 Dec;73(12):2168-73. doi: 10.1136/annrheumdis-2013-203666. Epub 2013 Sep 11. Ann Rheum Dis. 2014. PMID: 24026675 Free PMC article.
Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes.
De Benedetti F, Gattorno M, Anton J, Ben-Chetrit E, Frenkel J, Hoffman HM, Koné-Paut I, Lachmann HJ, Ozen S, Simon A, Zeft A, Calvo Penades I, Moutschen M, Quartier P, Kasapcopur O, Shcherbina A, Hofer M, Hashkes PJ, Van der Hilst J, Hara R, Bujan-Rivas S, Constantin T, Gul A, Livneh A, Brogan P, Cattalini M, Obici L, Lheritier K, Speziale A, Junge G. De Benedetti F, et al. Among authors: frenkel j. N Engl J Med. 2018 May 17;378(20):1908-1919. doi: 10.1056/NEJMoa1706314. N Engl J Med. 2018. PMID: 29768139 Clinical Trial.
Periodic fever in MVK deficiency: a patient initially diagnosed with incomplete Kawasaki disease.
Thors VS, Vastert SJ, Wulffraat N, van Royen A, Frenkel J, de Sain-van der Velden M, de Koning TJ. Thors VS, et al. Among authors: frenkel j. Pediatrics. 2014 Feb;133(2):e461-5. doi: 10.1542/peds.2012-1372. Epub 2014 Jan 27. Pediatrics. 2014. PMID: 24470648
Unprenylated RhoA contributes to IL-1β hypersecretion in mevalonate kinase deficiency model through stimulation of Rac1 activity.
van der Burgh R, Pervolaraki K, Turkenburg M, Waterham HR, Frenkel J, Boes M. van der Burgh R, et al. Among authors: frenkel j. J Biol Chem. 2014 Oct 3;289(40):27757-65. doi: 10.1074/jbc.M114.571810. Epub 2014 Aug 8. J Biol Chem. 2014. PMID: 25107911 Free PMC article.
Treatment of hereditary autoinflammatory diseases.
Ter Haar NM, Frenkel J. Ter Haar NM, et al. Among authors: frenkel j. Curr Opin Rheumatol. 2014 May;26(3):252-8. doi: 10.1097/BOR.0000000000000059. Curr Opin Rheumatol. 2014. PMID: 24667287 Review.
Mevalonate kinase deficiency, a metabolic autoinflammatory disease.
van der Burgh R, Ter Haar NM, Boes ML, Frenkel J. van der Burgh R, et al. Among authors: frenkel j. Clin Immunol. 2013 Jun;147(3):197-206. doi: 10.1016/j.clim.2012.09.011. Epub 2012 Oct 4. Clin Immunol. 2013. PMID: 23110805 Review.
A role for geranylgeranylation in interleukin-1beta secretion.
Mandey SH, Kuijk LM, Frenkel J, Waterham HR. Mandey SH, et al. Among authors: frenkel j. Arthritis Rheum. 2006 Nov;54(11):3690-5. doi: 10.1002/art.22194. Arthritis Rheum. 2006. PMID: 17075828
Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.
Kuijk LM, Mandey SH, Schellens I, Waterham HR, Rijkers GT, Coffer PJ, Frenkel J. Kuijk LM, et al. Among authors: frenkel j. Mol Immunol. 2008 Apr;45(8):2158-65. doi: 10.1016/j.molimm.2007.12.008. Epub 2008 Feb 1. Mol Immunol. 2008. PMID: 18242710
Hyperimmunoglobulin D syndrome in childhood.
van der Hilst JC, Frenkel J. van der Hilst JC, et al. Among authors: frenkel j. Curr Rheumatol Rep. 2010 Apr;12(2):101-7. doi: 10.1007/s11926-010-0086-1. Curr Rheumatol Rep. 2010. PMID: 20425018 Review.
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