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Determination of human NAT2 acetylator genotype by restriction fragment-length polymorphism and allele-specific amplification.
Doll MA, Fretland AJ, Deitz AC, Hein DW. Doll MA, et al. Among authors: fretland aj. Anal Biochem. 1995 Nov 1;231(2):413-20. doi: 10.1006/abio.1995.9978. Anal Biochem. 1995. PMID: 8594994
Acetylator phenotype and genotype in HIV-infected patients with and without sulfonamide hypersensitivity.
O'Neil WM, MacArthur RD, Farrough MJ, Doll MA, Fretland AJ, Hein DW, Crane LR, Svensson CK. O'Neil WM, et al. Among authors: fretland aj. J Clin Pharmacol. 2002 Jun;42(6):613-9. doi: 10.1177/00970002042006004. J Clin Pharmacol. 2002. PMID: 12043950
Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster.
Hein DW, Doll MA, Nerland DE, Fretland AJ. Hein DW, et al. Among authors: fretland aj. Mol Carcinog. 2006 Apr;45(4):230-8. doi: 10.1002/mc.20164. Mol Carcinog. 2006. PMID: 16482518
Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
Hein DW, Fretland AJ, Doll MA. Hein DW, et al. Among authors: fretland aj. Int J Cancer. 2006 Sep 1;119(5):1208-11. doi: 10.1002/ijc.21957. Int J Cancer. 2006. PMID: 16570281 Free PMC article.
Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition.
Fretland AJ, Doll MA, Zhu Y, Smith L, Leff MA, Hein DW. Fretland AJ, et al. Cancer Detect Prev. 2002;26(1):10-4. doi: 10.1016/s0361-090x(02)00005-3. Cancer Detect Prev. 2002. PMID: 12088197
Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
Fretland AJ, Devanaboyina US, Doll MA, Zhao S, Xiao GH, Hein DW. Fretland AJ, et al. Toxicol Sci. 2003 Aug;74(2):253-9. doi: 10.1093/toxsci/kfg133. Epub 2003 May 28. Toxicol Sci. 2003. PMID: 12773763
Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.
Fretland AJ, Doll MA, Leff MA, Hein DW. Fretland AJ, et al. Pharmacogenetics. 2001 Aug;11(6):511-20. doi: 10.1097/00008571-200108000-00006. Pharmacogenetics. 2001. PMID: 11505221
Oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) yields PhIP-DNA adducts but not tumors in male Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
Fretland AJ, Devanaboyina US, Feng Y, Leff MA, Xiao GH, Webb SJ, Hein DW. Fretland AJ, et al. Toxicol Sci. 2001 Feb;59(2):226-30. doi: 10.1093/toxsci/59.2.226. Toxicol Sci. 2001. PMID: 11158715
Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.
Hein DW, Doll MA, Fretland AJ, Leff MA, Webb SJ, Xiao GH, Devanaboyina US, Nangju NA, Feng Y. Hein DW, et al. Among authors: fretland aj. Cancer Epidemiol Biomarkers Prev. 2000 Jan;9(1):29-42. Cancer Epidemiol Biomarkers Prev. 2000. PMID: 10667461 Review.
Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse.
Leff MA, Epstein PN, Doll MA, Fretland AJ, Devanaboyina US, Rustan TD, Hein DW. Leff MA, et al. Among authors: fretland aj. J Pharmacol Exp Ther. 1999 Jul;290(1):182-7. J Pharmacol Exp Ther. 1999. PMID: 10381774
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