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Mitochondrial permeability transition in acute neurodegeneration.
Friberg H, Wieloch T. Friberg H, et al. Biochimie. 2002 Feb-Mar;84(2-3):241-50. doi: 10.1016/s0300-9084(02)01381-0. Biochimie. 2002. PMID: 12022955 Review.
The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.
Drake M, Friberg H, Boris-Möller F, Sakata K, Wieloch T. Drake M, et al. Among authors: friberg h. Acta Physiol Scand. 1996 Oct;158(2):155-9. doi: 10.1046/j.1365-201X.1996.535298000.x. Acta Physiol Scand. 1996. PMID: 8899062
Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.
Friberg H, Ferrand-Drake M, Bengtsson F, Halestrap AP, Wieloch T. Friberg H, et al. J Neurosci. 1998 Jul 15;18(14):5151-9. doi: 10.1523/JNEUROSCI.18-14-05151.1998. J Neurosci. 1998. PMID: 9651198 Free PMC article.
Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia.
Ferrand-Drake M, Friberg H, Wieloch T. Ferrand-Drake M, et al. Among authors: friberg h. Neuroscience. 1999;90(4):1325-38. doi: 10.1016/s0306-4522(98)00559-4. Neuroscience. 1999. PMID: 10338300
Cell nuclei displayed terminal deoxynucleotidyl transferase-deoxyuridine triphosphate nick-end labelling within 3 h of recovery following 30 min of a hypoglycemic insult, and DNA from the hippocampus displayed oligonucleosomal fragmentation. ...
Cell nuclei displayed terminal deoxynucleotidyl transferase-deoxyuridine triphosphate nick-end labelling within 3 h of recovery follo …
Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion.
Matsumoto S, Friberg H, Ferrand-Drake M, Wieloch T. Matsumoto S, et al. Among authors: friberg h. J Cereb Blood Flow Metab. 1999 Jul;19(7):736-41. doi: 10.1097/00004647-199907000-00002. J Cereb Blood Flow Metab. 1999. PMID: 10413027
Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons.
Khaspekov L, Friberg H, Halestrap A, Viktorov I, Wieloch T. Khaspekov L, et al. Among authors: friberg h. Eur J Neurosci. 1999 Sep;11(9):3194-8. doi: 10.1046/j.1460-9568.1999.00743.x. Eur J Neurosci. 1999. PMID: 10510183
When mouse hippocampal neuronal cultures, 2-3 weeks in vitro, were transiently exposed to combined glucose and oxygen deprivation (100% argon, 5% CO2, in glucose-free medium) for 90 min, extensive neuronal degeneration had occurred after 24 h of reoxygenation. ...
When mouse hippocampal neuronal cultures, 2-3 weeks in vitro, were transiently exposed to combined glucose and oxygen deprivation (100% argo …
Mitochondrial oxidative stress after global brain ischemia in rats.
Friberg H, Wieloch T, Castilho RF. Friberg H, et al. Neurosci Lett. 2002 Dec 13;334(2):111-4. doi: 10.1016/s0304-3940(02)01116-3. Neurosci Lett. 2002. PMID: 12435484
In the present study, rat brain mitochondria were isolated at different time points (4 h, 24 h and 48 h) after transient global ischemia. Detection of mitochondrially-generated reactive oxygen species, measured through dichlorodihydrofluorescein oxidation, wa …
In the present study, rat brain mitochondria were isolated at different time points (4 h, 24 h and 48 h) after transien …
Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria.
Hansson MJ, Persson T, Friberg H, Keep MF, Rees A, Wieloch T, Elmér E. Hansson MJ, et al. Among authors: friberg h. Brain Res. 2003 Jan 17;960(1-2):99-111. doi: 10.1016/s0006-8993(02)03798-8. Brain Res. 2003. PMID: 12505662
Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation.
Mattiasson G, Friberg H, Hansson M, Elmér E, Wieloch T. Mattiasson G, et al. Among authors: friberg h. J Neurochem. 2003 Oct;87(2):532-44. doi: 10.1046/j.1471-4159.2003.02026.x. J Neurochem. 2003. PMID: 14511130
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