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Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus.
Frick LW, St John L, Taylor LC, Painter GR, Furman PA, Liotta DC, Furfine ES, Nelson DJ. Frick LW, et al. Antimicrob Agents Chemother. 1993 Nov;37(11):2285-92. doi: 10.1128/AAC.37.11.2285. Antimicrob Agents Chemother. 1993. PMID: 8285607 Free PMC article.
Synthesis of novel anilinoquinolines as c-fms inhibitors.
Smalley TL Jr, Chamberlain SD, Mills WY, Musso DL, Randhawa SA, Ray JA, Samano V, Frick L. Smalley TL Jr, et al. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6257-60. doi: 10.1016/j.bmcl.2007.09.009. Epub 2007 Sep 7. Bioorg Med Chem Lett. 2007. PMID: 17870531
Synthesis and evaluation of a series of 2'-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94).
Chan JH, Chamberlain SD, Biron KK, Davis MG, Harvey RJ, Selleseth DW, Dornsife RE, Dark EH, Frick LW, Townsend LB, Drach JC, Koszalka GW. Chan JH, et al. Among authors: frick lw. Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):101-23. doi: 10.1080/15257770008032999. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 10772705
The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Furman PA, Davis M, Liotta DC, Paff M, Frick LW, Nelson DJ, Dornsife RE, Wurster JA, Wilson LJ, Fyfe JA, et al. Furman PA, et al. Among authors: frick lw. Antimicrob Agents Chemother. 1992 Dec;36(12):2686-92. doi: 10.1128/AAC.36.12.2686. Antimicrob Agents Chemother. 1992. PMID: 1336341 Free PMC article.
In vivo antiviral activity and pharmacokinetics of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in woodchuck hepatitis virus-infected woodchucks.
Cullen JM, Smith SL, Davis MG, Dunn SE, Botteron C, Cecchi A, Linsey D, Linzey D, Frick L, Paff MT, Goulding A, Biron K. Cullen JM, et al. Antimicrob Agents Chemother. 1997 Oct;41(10):2076-82. doi: 10.1128/AAC.41.10.2076. Antimicrob Agents Chemother. 1997. PMID: 9333028 Free PMC article.
25 results