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The housekeeping gene hypoxanthine guanine phosphoribosyltransferase (HPRT) regulates multiple developmental and metabolic pathways of murine embryonic stem cell neuronal differentiation.
Kang TH, Park Y, Bader JS, Friedmann T. Kang TH, et al. Among authors: friedmann t. PLoS One. 2013 Oct 9;8(10):e74967. doi: 10.1371/journal.pone.0074967. eCollection 2013. PLoS One. 2013. PMID: 24130677 Free PMC article.
Bone marrow transplantation does not ameliorate the neurologic symptoms in mice deficient in hypoxanthine guanine phosphoribosyl transferase (HPRT).
Wojcik BE, Jinnah HA, Muller-Sieburg CE, Friedmann T. Wojcik BE, et al. Among authors: friedmann t. Metab Brain Dis. 1999 Mar;14(1):57-65. doi: 10.1023/a:1020661514514. Metab Brain Dis. 1999. PMID: 10348314
Brain purines in a genetic mouse model of Lesch-Nyhan disease.
Jinnah HA, Page T, Friedmann T. Jinnah HA, et al. Among authors: friedmann t. J Neurochem. 1993 Jun;60(6):2036-45. doi: 10.1111/j.1471-4159.1993.tb03488.x. J Neurochem. 1993. PMID: 8492116
Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Jinnah HA, Wojcik BE, Hunt M, Narang N, Lee KY, Goldstein M, Wamsley JK, Langlais PJ, Friedmann T. Jinnah HA, et al. Among authors: friedmann t. J Neurosci. 1994 Mar;14(3 Pt 1):1164-75. doi: 10.1523/JNEUROSCI.14-03-01164.1994. J Neurosci. 1994. PMID: 7509865 Free PMC article.
Adult mammalian hepatocyte as target cell for retroviral gene transfer: a model for gene therapy.
Wolff JA, Yee JK, Skelly H, Moores J, Respess J, Friedmann T, Leffert H. Wolff JA, et al. Among authors: friedmann t. Somat Cell Mol Genet. 1987 Jul;13(4):423-8. doi: 10.1007/BF01534943. Somat Cell Mol Genet. 1987. PMID: 3484086 No abstract available.
Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferase.
Jolly DJ, Esty AC, Bernard HU, Friedmann T. Jolly DJ, et al. Among authors: friedmann t. Proc Natl Acad Sci U S A. 1982 Aug;79(16):5038-41. doi: 10.1073/pnas.79.16.5038. Proc Natl Acad Sci U S A. 1982. PMID: 6956912 Free PMC article.
A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.
Miller AD, Jolly DJ, Friedmann T, Verma IM. Miller AD, et al. Among authors: friedmann t. Proc Natl Acad Sci U S A. 1983 Aug;80(15):4709-13. doi: 10.1073/pnas.80.15.4709. Proc Natl Acad Sci U S A. 1983. PMID: 6308645 Free PMC article.
MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease?
Guibinga GH, Hrustanovic G, Bouic K, Jinnah HA, Friedmann T. Guibinga GH, et al. Among authors: friedmann t. Hum Mol Genet. 2012 Feb 1;21(3):609-22. doi: 10.1093/hmg/ddr495. Epub 2011 Oct 31. Hum Mol Genet. 2012. PMID: 22042773 Free PMC article.
HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?
Kang TH, Guibinga GH, Jinnah HA, Friedmann T. Kang TH, et al. Among authors: friedmann t. PLoS One. 2011 Jan 28;6(1):e16572. doi: 10.1371/journal.pone.0016572. PLoS One. 2011. PMID: 21305049 Free PMC article.
Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression.
Tsimikas S, Miyanohara A, Hartvigsen K, Merki E, Shaw PX, Chou MY, Pattison J, Torzewski M, Sollors J, Friedmann T, Lai NC, Hammond HK, Getz GS, Reardon CA, Li AC, Banka CL, Witztum JL. Tsimikas S, et al. Among authors: friedmann t. J Am Coll Cardiol. 2011 Oct 11;58(16):1715-27. doi: 10.1016/j.jacc.2011.07.017. J Am Coll Cardiol. 2011. PMID: 21982317 Free PMC article.
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