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A stratified two-stage tumor molecular profiling algorithm to identify clinically actionable molecular alterations in pancreatic cancer.
Hussung S, Akhoundova D, Pistoni C, Lenggenhager D, Töpfer A, Pauli C, Pestalozzi B, Britschgi C, Zoche M, Rechsteiner M, Moch H, Weber A, Fritsch R. Hussung S, et al. Among authors: fritsch r. ESMO Gastrointest Oncol. 2025 Feb 10;7:100134. doi: 10.1016/j.esmogo.2025.100134. eCollection 2025 Mar. ESMO Gastrointest Oncol. 2025. PMID: 41646477 Free PMC article.
Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease.
Morsy Y, Walberg Å, Wawrzyniak P, Hubeli B, Truscello L, Mamie C, Niechcial A, Gueguen E, Manzini R, Gottier C, Lang S, Scharl S, Blümel S, Biedermann L, Rogler G, Turina M, Ramser M, Petrowsky H, Arnold IC, Zeissig S, Zamboni N, Egli A, Niess JH, Hruz P, Knuth A, Fritsch R, Manz MG, Wawrzyniak M, Scharl M. Morsy Y, et al. Among authors: fritsch r. Gut Microbes. 2025 Dec;17(1):2530157. doi: 10.1080/19490976.2025.2530157. Epub 2025 Jul 20. Gut Microbes. 2025. PMID: 40685618 Free PMC article.
Recommendations on Perihilar Cholangiocarcinoma. The Milan Jury-Based Consensus.
Pfister M, Ratti F, Gores GJ, Lesurtel M, Chiche L, Ebata T, Ardiles V, Valle JW, Heimbach JK, Braconi C, Bruix J, Aldrighetti L, Clavien PA; Consensus4pCCA Collaborative. Pfister M, et al. Ann Surg. 2025 Jun 6. doi: 10.1097/SLA.0000000000006773. Online ahead of print. Ann Surg. 2025. PMID: 40478744
BRAFΔβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability.
Lauinger M, Christen D, Klar RFU, Roubaty C, Heilig CE, Stumpe M, Knox JJ, Radulovich N, Tamblyn L, Xie IY, Horak P, Forschner A, Bitzer M, Wittel UA, Boerries M, Ball CR, Heining C, Glimm H, Fröhlich M, Hübschmann D, Gallinger S, Fritsch R, Fröhling S, O'Kane GM, Dengjel J, Brummer T. Lauinger M, et al. Among authors: fritsch r. Sci Adv. 2023 Sep;9(35):eade7486. doi: 10.1126/sciadv.ade7486. Epub 2023 Sep 1. Sci Adv. 2023. PMID: 37656784 Free PMC article.
Ablatio-bilica: safety of biliary intraductal radiofrequency ablation in patients with unresectable extrahepatic biliary tract cancer undergoing systemic anti-tumor therapy: a phase II, multi-center, randomized, and controlled study.
Pfister T, Chan SCW, Trelle S, Bütikofer S, Winterhalder R, Koessler T, Schlag C, Fritsch R, Frossard JL, Moser A, Berger MD, Wiest R. Pfister T, et al. Among authors: fritsch r. Front Oncol. 2026 Feb 24;15:1576401. doi: 10.3389/fonc.2025.1576401. eCollection 2025. Front Oncol. 2026. PMID: 41816011 Free PMC article.
Nivolumab combination therapies in patients with advanced gastric and gastroesophageal junction cancer: the phase II FRACTION gastric cancer study.
Ku G, Haag GM, Park H, Lam VK, George TJ, Kim SS, Gutierrez M, Shankaran V, Stein S, Denlinger CS, Elimova E, Nagrial A, He AR, Sawyer MB, Yoon HH, Geva R, Starr J, Curigliano G, Golan T, von Moos R, Fritsch R, Lim D, Wang Q, Patel A, Aoyama T, Lei M, Greenawalt D, Di Bartolomeo M. Ku G, et al. Among authors: fritsch r. ESMO Open. 2025 Feb;10(2):104107. doi: 10.1016/j.esmoop.2024.104107. Epub 2025 Jan 10. ESMO Open. 2025. PMID: 39798422 Free PMC article. Clinical Trial.
Benefit of Adjuvant Therapy After Neoadjuvant Therapy and Resection for Patients with Pancreatic Cancer: A Systematic Review and Meta-analysis.
Frey MC, Lopez-Lopez V, Benz A, Abdurakhmonov S, Amirian H, Datta J, Lee SH, Yoo C, Pu N, Zhang C, Reames BN, Fritsch R, Petrowsky H, Oberholzer J, Eshmuminov D. Frey MC, et al. Among authors: fritsch r. Ann Surg Oncol. 2026 Jun 3. doi: 10.1245/s10434-026-19841-5. Online ahead of print. Ann Surg Oncol. 2026. PMID: 42236648
272 results