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Rho GTPases are over-expressed in human tumors.
Fritz G, Just I, Kaina B. Fritz G, et al. Int J Cancer. 1999 May 31;81(5):682-7. doi: 10.1002/(sici)1097-0215(19990531)81:5<682::aid-ijc2>;2-b. Int J Cancer. 1999. PMID: 10328216
Rho inhibition by lovastatin affects apoptosis and DSB repair of primary human lung cells in vitro and lung tissue in vivo following fractionated irradiation.
Ziegler V, Henninger C, Simiantonakis I, Buchholzer M, Ahmadian MR, Budach W, Fritz G. Ziegler V, et al. Among authors: fritz g. Cell Death Dis. 2017 Aug 10;8(8):e2978. doi: 10.1038/cddis.2017.372. Cell Death Dis. 2017. PMID: 28796249 Free PMC article.
Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1.
Huelsenbeck SC, Roggenkamp D, May M, Huelsenbeck J, Brakebusch C, Rottner K, Ladwein M, Just I, Fritz G, Schmidt G, Genth H. Huelsenbeck SC, et al. Among authors: fritz g. Int J Biochem Cell Biol. 2013 Aug;45(8):1767-75. doi: 10.1016/j.biocel.2013.05.020. Epub 2013 May 31. Int J Biochem Cell Biol. 2013. PMID: 23732113
Cytoprotective effect of the small GTPase RhoB expressed upon treatment of fibroblasts with the Ras-glucosylating Clostridium sordellii lethal toxin.
Huelsenbeck J, May M, Schulz F, Schelle I, Ronkina N, Hohenegger M, Fritz G, Just I, Gerhard R, Genth H. Huelsenbeck J, et al. Among authors: fritz g. FEBS Lett. 2012 Oct 19;586(20):3665-73. doi: 10.1016/j.febslet.2012.08.024. Epub 2012 Sep 11. FEBS Lett. 2012. PMID: 22982107
Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.
Gerhard R, Tatge H, Genth H, Thum T, Borlak J, Fritz G, Just I. Gerhard R, et al. Among authors: fritz g. J Biol Chem. 2005 Jan 14;280(2):1499-505. doi: 10.1074/jbc.M406014200. Epub 2004 Nov 5. J Biol Chem. 2005. PMID: 15531589
DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).
Damrot J, Helbig L, Roos WP, Barrantes SQ, Kaina B, Fritz G. Damrot J, et al. Among authors: fritz g. J Mol Biol. 2009 Feb 6;385(5):1409-21. doi: 10.1016/j.jmb.2008.12.015. Epub 2008 Dec 14. J Mol Biol. 2009. PMID: 19109974
DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac.
Wartlick F, Bopp A, Henninger C, Fritz G. Wartlick F, et al. Among authors: fritz g. Biochim Biophys Acta. 2013 Dec;1833(12):3093-3103. doi: 10.1016/j.bbamcr.2013.08.016. Epub 2013 Aug 30. Biochim Biophys Acta. 2013. PMID: 23999236
Lovastatin stimulates p75 TNF receptor (TNFR2) expression in primary human endothelial cells.
Nübel T, Schmitt S, Kaina B, Fritz G. Nübel T, et al. Among authors: fritz g. Int J Mol Med. 2005 Dec;16(6):1139-45. Int J Mol Med. 2005. PMID: 16273297
Nuclear expression of apurinic/apyrimidinic endonuclease increases with progression of ovarian carcinomas.
Tanner B, Grimme S, Schiffer I, Heimerdinger C, Schmidt M, Dutkowski P, Neubert S, Oesch F, Franzen A, Kölbl H, Fritz G, Kaina B, Hengstler JG. Tanner B, et al. Among authors: fritz g. Gynecol Oncol. 2004 Feb;92(2):568-77. doi: 10.1016/j.ygyno.2003.10.037. Gynecol Oncol. 2004. PMID: 14766249
Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells.
Trost TM, Lausch EU, Fees SA, Schmitt S, Enklaar T, Reutzel D, Brixel LR, Schmidtke P, Maringer M, Schiffer IB, Heimerdinger CK, Hengstler JG, Fritz G, Bockamp EO, Prawitt D, Zabel BU, Spangenberg C. Trost TM, et al. Among authors: fritz g. Cancer Res. 2005 Feb 1;65(3):840-9. Cancer Res. 2005. PMID: 15705882
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