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791 results

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Page 1
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, Balkau B, Benediktsson R, Bergman RN, Boerwinkle E, Bonnycastle L, Burtt NP, Campbell H, Charpentier G, Collins FS, Gieger C, Green T, Hadjadj S, Hattersley AT, Herder C, Hofman A, Johnson AD, Kottgen A, Kraft P, Labrune Y, Langenberg C, Manning AK, Mohlke KL, Morris AP, Oostra B, Pankow J, Petersen AK, Pramstaller PP, Prokopenko I, Rathmann W, Rayner W, Roden M, Rudan I, Rybin D, Scott LJ, Sigurdsson G, Sladek R, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Uitterlinden AG, Vivequin S, Weedon MN, Wright AF; MAGIC; DIAGRAM Consortium; GIANT Consortium; Hu FB, Illig T, Kao L, Meigs JB, Wilson JF, Stefansson K, van Duijn C, Altschuler D, Morris AD, Boehnke M, McCarthy MI, Froguel P, Palmer CN, Wareham NJ, Groop L, Frayling TM, Cauchi S. Perry JR, et al. Among authors: froguel p. PLoS Genet. 2012 May;8(5):e1002741. doi: 10.1371/journal.pgen.1002741. Epub 2012 May 31. PLoS Genet. 2012. PMID: 22693455 Free PMC article.
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
Frayling TM, Lindgren CM, Chevre JC, Menzel S, Wishart M, Benmezroua Y, Brown A, Evans JC, Rao PS, Dina C, Lecoeur C, Kanninen T, Almgren P, Bulman MP, Wang Y, Mills J, Wright-Pascoe R, Mahtani MM, Prisco F, Costa A, Cognet I, Hansen T, Pedersen O, Ellard S, Tuomi T, Groop LC, Froguel P, Hattersley AT, Vaxillaire M. Frayling TM, et al. Among authors: froguel p. Diabetes. 2003 Mar;52(3):872-81. doi: 10.2337/diabetes.52.3.872. Diabetes. 2003. PMID: 12606533
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
Demenais F, Kanninen T, Lindgren CM, Wiltshire S, Gaget S, Dandrieux C, Almgren P, Sjögren M, Hattersley A, Dina C, Tuomi T, McCarthy MI, Froguel P, Groop LC. Demenais F, et al. Among authors: froguel p. Hum Mol Genet. 2003 Aug 1;12(15):1865-73. doi: 10.1093/hmg/ddg195. Hum Mol Genet. 2003. PMID: 12874106
Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study.
Fumeron F, Aubert R, Siddiq A, Betoulle D, Péan F, Hadjadj S, Tichet J, Wilpart E, Chesnier MC, Balkau B, Froguel P, Marre M; Epidemiologic Data on the Insulin Resistance Syndrome (DESIR) Study Group. Fumeron F, et al. Among authors: froguel p. Diabetes. 2004 Apr;53(4):1150-7. doi: 10.2337/diabetes.53.4.1150. Diabetes. 2004. PMID: 15047634
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
Meyre D, Bouatia-Naji N, Tounian A, Samson C, Lecoeur C, Vatin V, Ghoussaini M, Wachter C, Hercberg S, Charpentier G, Patsch W, Pattou F, Charles MA, Tounian P, Clément K, Jouret B, Weill J, Maddux BA, Goldfine ID, Walley A, Boutin P, Dina C, Froguel P. Meyre D, et al. Among authors: froguel p. Nat Genet. 2005 Aug;37(8):863-7. doi: 10.1038/ng1604. Epub 2005 Jul 17. Nat Genet. 2005. PMID: 16025115 Free PMC article.
Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses.
Tsuchiya T, Schwarz PE, Bosque-Plata LD, Geoffrey Hayes M, Dina C, Froguel P, Wayne Towers G, Fischer S, Temelkova-Kurktschiev T, Rietzsch H, Graessler J, Vcelák J, Palyzová D, Selisko T, Bendlová B, Schulze J, Julius U, Hanefeld M, Weedon MN, Evans JC, Frayling TM, Hattersley AT, Orho-Melander M, Groop L, Malecki MT, Hansen T, Pedersen O, Fingerlin TE, Boehnke M, Hanis CL, Cox NJ, Bell GI. Tsuchiya T, et al. Among authors: froguel p. Mol Genet Metab. 2006 Sep-Oct;89(1-2):174-84. doi: 10.1016/j.ymgme.2006.05.013. Epub 2006 Jul 11. Mol Genet Metab. 2006. PMID: 16837224
791 results