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High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).
Niemi M, Schaeffeler E, Lang T, Fromm MF, Neuvonen M, Kyrklund C, Backman JT, Kerb R, Schwab M, Neuvonen PJ, Eichelbaum M, Kivistö KT. Niemi M, et al. Among authors: fromm mf. Pharmacogenetics. 2004 Jul;14(7):429-40. doi: 10.1097/01.fpc.0000114750.08559.32. Pharmacogenetics. 2004. PMID: 15226675
Genetic polymorphisms of the human MDR1 drug transporter.
Schwab M, Eichelbaum M, Fromm MF. Schwab M, et al. Among authors: fromm mf. Annu Rev Pharmacol Toxicol. 2003;43:285-307. doi: 10.1146/annurev.pharmtox.43.100901.140233. Epub 2002 Jan 10. Annu Rev Pharmacol Toxicol. 2003. PMID: 12359865 Review.
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