Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

28 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense.
Frommel TO, Balber AE. Frommel TO, et al. Mol Biochem Parasitol. 1987 Nov;26(1-2):183-91. doi: 10.1016/0166-6851(87)90142-3. Mol Biochem Parasitol. 1987. PMID: 3431564
Clones selected for resistance to melarsoprol were shown to be cross-resistant in vivo to two diamidines, pentamidine and Berenil, but not to suramin. ...Drug concentrations giving half-maximal rates of accumulation were increased in the resistant clon …
Clones selected for resistance to melarsoprol were shown to be cross-resistant in vivo to two diamidines, pentamidine a …
Trypanosoma brucei gambiense and T. b. rhodesiense: concanavalin A binding to the membrane and flagellar pocket of bloodstream and procyclic forms.
Balber AE, Frommel TO. Balber AE, et al. J Protozool. 1988 May;35(2):214-9. doi: 10.1111/j.1550-7408.1988.tb04326.x. J Protozool. 1988. PMID: 3397913
We have measured binding of fluorescein-conjugated succinyl-concanavalin A (Fl-s-Con A) to bloodstream and procyclic forms of Trypanosoma brucei gambiense and to bloodstream forms of T. b. rhodesiense by flow cytofluorimetry. ...Microscopically detectable Fl-s-Con A …
We have measured binding of fluorescein-conjugated succinyl-concanavalin A (Fl-s-Con A) to bloodstream and procyclic forms of Trypano …
Changes in albumin levels in blood and urine of Microtus montanus chronically infected with Trypanosoma brucei gambiense.
Frommel TO, Seed JR, Sechelski J. Frommel TO, et al. J Parasitol. 1988 Dec;74(6):957-62. J Parasitol. 1988. PMID: 3057169
This relative resistance was most likely due to the fact that female animals were relatively more efficient in limiting parasitemia during the first week of infection. ...
This relative resistance was most likely due to the fact that female animals were relatively more efficient in limiting parasitemia d …
Trypanosoma brucei sspp.: cleavage of variant specific and common glycoproteins during exposure of live cells to trypsin.
Frommel TO, Seyfang A, Balber AE. Frommel TO, et al. Exp Parasitol. 1988 Aug;66(2):213-24. doi: 10.1016/0014-4894(88)90093-8. Exp Parasitol. 1988. PMID: 2456221
The removal of VSG was coincident with appearance of 37 to 50 kDa glycopeptide fragments of VSG with different clones yielding different sized fragments. ...Antiserum to the cross-reactive determinant bound to intact VSG, but did not bind VSG fragments. Thus, …
The removal of VSG was coincident with appearance of 37 to 50 kDa glycopeptide fragments of VSG with different clones yielding differ …
Trypanosoma brucei brucei and Trypanosoma brucei gambiense: stage specific differences in wheat germ agglutinin binding and in endoglycosidase H sensitivity of glycoprotein oligosaccharides.
Frommel TO, Kohler MF, Balber AE. Frommel TO, et al. Exp Parasitol. 1987 Aug;64(1):104-10. doi: 10.1016/0014-4894(87)90014-2. Exp Parasitol. 1987. PMID: 2440711
Silver staining showed, as expected, that the expression of the variant specific glycoprotein was restricted to the bloodstream forms. ...Incubating transferred proteins in endoglycosidase H eliminated subsequent binding of concanavalin A to most of the 22 common gl …
Silver staining showed, as expected, that the expression of the variant specific glycoprotein was restricted to the bloodstream forms …
Tissue alterations in Microtus montanus chronically infected with Trypanosoma brucei gambiense.
Frommel TO, Fujikura Y, Seed JR. Frommel TO, et al. J Parasitol. 1991 Feb;77(1):164-7. J Parasitol. 1991. PMID: 1992088
An increase in body weight of infected animals was attributable to a significant increase in total mass of spleen, liver and kidney. ...
An increase in body weight of infected animals was attributable to a significant increase in total mass of spleen, liver and kidney. …
Trypanosoma brucei brucei, T. brucei gambiense, and T. brucei rhodesiense: common glycoproteins and glycoprotein oligosaccharide heterogeneity identified by lectin affinity blotting and endoglycosidase H treatment.
Frommel TO, Balber AE. Frommel TO, et al. Exp Parasitol. 1987 Feb;63(1):32-41. doi: 10.1016/0014-4894(87)90075-0. Exp Parasitol. 1987. PMID: 2433150
Prior incubation of blots in endo-beta-N-acetylglucosaminidase H eliminated binding of peroxidase-labeled concanavalin A to most of the 22 common glycoproteins. ...Endoglycosidase H treatment also reduced binding of peroxidase labeled concanavalin A to the variant s …
Prior incubation of blots in endo-beta-N-acetylglucosaminidase H eliminated binding of peroxidase-labeled concanavalin A to most of t …
The major surface glycoprotein (GP63) is present in both life stages of Leishmania.
Frommel TO, Button LL, Fujikura Y, McMaster WR. Frommel TO, et al. Mol Biochem Parasitol. 1990 Jan 1;38(1):25-32. doi: 10.1016/0166-6851(90)90201-v. Mol Biochem Parasitol. 1990. PMID: 2181303
Promastigotes express a major surface glycoprotein of 63 kDa, referred to as GP63. The expression of GP63 in both Leishmania life stages was studied using rabbit antibodies against native GP63 as well as rabbit antibodies against recombinant GP63 that was synthesized in an …
Promastigotes express a major surface glycoprotein of 63 kDa, referred to as GP63. The expression of GP63 in both Leishmania life sta …
Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection.
Choi K, Frommel TO, Stern RK, Perez CF, Kriegler M, Tsuruo T, Roninson IB. Choi K, et al. Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7386-90. doi: 10.1073/pnas.88.16.7386. Proc Natl Acad Sci U S A. 1991. PMID: 1678523 Free PMC article.
To determine whether cytotoxic selection contributes to the MDR phenotype of MDR1-expressing cells, NIH 3T3 cells infected with a recombinant retrovirus carrying the human MDR1 gene were selected by two different procedures: (i) noncytotoxic selection for increased
To determine whether cytotoxic selection contributes to the MDR phenotype of MDR1-expressing cells, NIH 3T3 cells infected wit
28 results
Jump to page
Feedback