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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.
Frye RA. Frye RA. Biochem Biophys Res Commun. 2000 Jul 5;273(2):793-8. doi: 10.1006/bbrc.2000.3000. Biochem Biophys Res Commun. 2000. PMID: 10873683
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
Frye RA. Frye RA. Biochem Biophys Res Commun. 1999 Jun 24;260(1):273-9. doi: 10.1006/bbrc.1999.0897. Biochem Biophys Res Commun. 1999. PMID: 10381378
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.
Langley E, Pearson M, Faretta M, Bauer UM, Frye RA, Minucci S, Pelicci PG, Kouzarides T. Langley E, et al. Among authors: frye ra. EMBO J. 2002 May 15;21(10):2383-96. doi: 10.1093/emboj/21.10.2383. EMBO J. 2002. PMID: 12006491 Free PMC article.
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. Vaziri H, et al. Among authors: frye ra. Cell. 2001 Oct 19;107(2):149-59. doi: 10.1016/s0092-8674(01)00527-x. Cell. 2001. PMID: 11672523 Free article.
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C, Frye R, Ploegh H, Kessler BM, Sinclair DA. Cohen HY, et al. Among authors: frye r. Mol Cell. 2004 Mar 12;13(5):627-38. doi: 10.1016/s1097-2765(04)00094-2. Mol Cell. 2004. PMID: 15023334
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.
Schwer B, North BJ, Frye RA, Ott M, Verdin E. Schwer B, et al. Among authors: frye ra. J Cell Biol. 2002 Aug 19;158(4):647-57. doi: 10.1083/jcb.200205057. Epub 2002 Aug 19. J Cell Biol. 2002. PMID: 12186850 Free PMC article.
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. Yeung F, et al. Among authors: frye ra. EMBO J. 2004 Jun 16;23(12):2369-80. doi: 10.1038/sj.emboj.7600244. Epub 2004 May 20. EMBO J. 2004. PMID: 15152190 Free PMC article.
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression.
Senawong T, Peterson VJ, Avram D, Shepherd DM, Frye RA, Minucci S, Leid M. Senawong T, et al. Among authors: frye ra. J Biol Chem. 2003 Oct 31;278(44):43041-50. doi: 10.1074/jbc.M307477200. Epub 2003 Aug 19. J Biol Chem. 2003. PMID: 12930829 Free PMC article.
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1).
van der Horst A, Tertoolen LG, de Vries-Smits LM, Frye RA, Medema RH, Burgering BM. van der Horst A, et al. Among authors: frye ra. J Biol Chem. 2004 Jul 9;279(28):28873-9. doi: 10.1074/jbc.M401138200. Epub 2004 May 4. J Biol Chem. 2004. PMID: 15126506 Free article.
SIRT1 regulates HIV transcription via Tat deacetylation.
Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M. Pagans S, et al. Among authors: frye r. PLoS Biol. 2005 Feb;3(2):e41. doi: 10.1371/journal.pbio.0030041. Epub 2005 Feb 8. PLoS Biol. 2005. PMID: 15719057 Free PMC article.
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